Principal Scientist, Biophysicist

Novartis • Annandale, NJ

33d • $108,500 - $222,300 • Onsite

About The Position

We are seeking a highly motivated and experienced Principal Scientist / Biophysicist to join our dynamic team in La Jolla, CA. You will work on-site full-time and bring deep expertise in biophysical assay development and high-throughput screening. If you have a passion for advancing scientific discovery and thrive in a fast-paced, collaborative, and cross-disciplinary environment, we encourage you to apply.

Requirements

• Ph.D. (post-doc preferred), in a relevant scientific discipline (e.g., Biophysics, Biochemistry, Bioengineering, or a related field), with 2+ years of industrial experience in drug discovery
• Deep expertise in designing, validating, executing and troubleshooting biophysical assays.
• Ability to manage multiple projects independently and adapt to evolving research priorities.
• Ability to innovate, keep up with the expanding field, recommend and bring in new technologies.
• Strong analytical, troubleshooting, and problem-solving skills.
• Excellent communication and teamwork abilities.

Nice To Haves

• Experience in integrating novel or emerging technologies into [high-throughput] screening workflows.
• Familiarity with data analysis software and electronic laboratory management systems.
• Hands-on experience with laboratory automation platforms and liquid handling systems.

Responsibilities

• Design, develop, and optimize biophysical assays (e.g., SPR, BLI) for characterization of small molecules.
• Execute routine assays for defining structure-activity relationships.
• Implement and manage automation solutions to enhance assay throughput and data quality.
• Collaborate with cross-functional teams to integrate new technologies and workflows into ongoing research projects.
• Analyze, interpret, and present scientific data to internal and external stakeholders.
• Maintain detailed laboratory records, contribute to the preparation of research reports and publications, and represent the team through internal presentations.

Benefits

• health, life and disability benefits
• a 401(k) with company contribution and match
• a variety of other benefits
• a generous time off package including vacation, personal days, holidays and other leaves

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree