Principal Scientist, Biophysicist

Novartis•Annandale, NJ

33d•$108,500 - $222,300•Onsite

About The Position

We are seeking a highly motivated and experienced Principal Scientist / Biophysicist to join our dynamic team in La Jolla, CA. You will work on-site full-time and bring deep expertise in biophysical assay development and high-throughput screening. If you have a passion for advancing scientific discovery and thrive in a fast-paced, collaborative, and cross-disciplinary environment, we encourage you to apply.

Requirements

Ph.D. (post-doc preferred), in a relevant scientific discipline (e.g., Biophysics, Biochemistry, Bioengineering, or a related field), with 2+ years of industrial experience in drug discovery
Deep expertise in designing, validating, executing and troubleshooting biophysical assays.
Ability to manage multiple projects independently and adapt to evolving research priorities.
Ability to innovate, keep up with the expanding field, recommend and bring in new technologies.
Strong analytical, troubleshooting, and problem-solving skills.
Excellent communication and teamwork abilities.

Nice To Haves

Experience in integrating novel or emerging technologies into [high-throughput] screening workflows.
Familiarity with data analysis software and electronic laboratory management systems.
Hands-on experience with laboratory automation platforms and liquid handling systems.

Responsibilities

Design, develop, and optimize biophysical assays (e.g., SPR, BLI) for characterization of small molecules.
Execute routine assays for defining structure-activity relationships.
Implement and manage automation solutions to enhance assay throughput and data quality.
Collaborate with cross-functional teams to integrate new technologies and workflows into ongoing research projects.
Analyze, interpret, and present scientific data to internal and external stakeholders.
Maintain detailed laboratory records, contribute to the preparation of research reports and publications, and represent the team through internal presentations.