Principal Research Scientist II
About The Position
AbbVie Parenteral Product Development Science & Technology (PDS&T) is a global organization responsible for all CMC activities related to the development and commercialization of AbbVie's parenteral products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologics medicines, including monoclonal antibodies, antibody drug conjugates (ADC), and other novel modalities, and spans from clinical proof of concept through commercial product launch. We are a world-class team of scientists and leaders driving the advancement of industry-leading analytical capabilities and AbbVie's pipeline of innovative medicines. Careers in AbbVie Parenteral PDS&T provide opportunities to work with global and cross-functional teams to develop innovative products and drive exceptional science. The Analytical Development group is responsible for programs that are transitioning from development stage to optimization and commercialization. We lead final method development, optimization, and validation, ensuring all analytical methods are fit for use in commercial QC laboratories. Additionally, we collaborate with the Drug Product Process Development groups to design and execute comprehensive studies that drive product and process understanding and support marketing application submission content. We are looking for a highly motivated person who can oversee process analytics within the Analytical Development team.
Requirements
- PhD (8+ years), Master’s Degree (14+ years), or Bachelor’s Degree (16+ years) in scientific discipline (e.g., Analytical Chemistry, Biochemistry, or Biology) with previous laboratory experience.
- Practical experience with troubleshooting methods, examining data wholistically, and guiding and advising scientists through study execution.
- Ability to multitask and work within timelines, delivering results in a team-oriented setting, and willing to work across scientific disciplines to drive programs through critical milestones.
- Demonstrated scientific writing skills and strong verbal communication skills, effectively organizing and presenting scientific plans and data.
Nice To Haves
- Practical experience and strong knowledge of protein HPLC (e.g., SEC, IEX, HIC), capillary electrophoresis, and other separation techniques as applied to protein analysis is preferred.
- Solid understanding of protein chemistry and biochemistry, particularly as related to biologics drug development, is preferred.
Responsibilities
- Works closely with the Drug Product team to coordinate analytical testing support for drug product process development studies.
- Develop study designs and testing plans in collaboration with the Drug Product Team and coordinate testing within the Analytical Team.
- Work with the outsourcing team to identify the appropriate third party lab, determine the scope of work to be outsourced, and coordinate test method transfer (as needed).
- Help coordinate sample shipments both coming into the analytical lab and shipping from the analytical lab.
- Review, assess, and interpret data relative to the samples generated for testing performed both internally and externally.
- Oversee activities, protocol generation, and communication of timelines and data generated as a key member of analytical subteams.
Benefits
- paid time off (vacation, holidays, sick)
- medical/dental/vision insurance
- 401(k)
- long-term incentive programs
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What This Job Offers
Job Type
Full-time
Career Level
Senior
