Principal Process Engineer, Lilly Medicine Foundry

Lilly • Indianapolis, IN

22h • $67,500 - $173,800

About The Position

Lilly is seeking a small molecule Process Engineer to support the pilot plant facility in Lebanon, Indiana, with a focus on active pharmaceutical ingredient (API) synthesis. The role provides technical support for small molecule drug substance manufacturing, including developing and sustaining process knowledge, solving equipment design challenges, optimizing processes, and managing equipment capabilities.

The position is part of the startup team for Lilly’s greenfield Medicine Foundry, an advanced research and manufacturing facility being built to produce API molecules for clinical trials. The engineer will help establish the processes and facility needed for a successful startup into GMP manufacturing operations. Initial work locations are Lilly Technology Center in Indianapolis or Parkwood West in Carmel, Indiana; the permanent location will be the new Lilly Medicine Foundry in Lebanon, Indiana.

Requirements

• Bachelor’s or master’s degree in Chemical Engineering or a related discipline.
• At least 4 years of experience in a pharmaceutical, biotech, chemical manufacturing, CMO, or other relevant batch manufacturing process environment.
• Must be authorized to work in the United States on a full-time basis; Lilly will not sponsor work authorization or visas for this role.

Nice To Haves

• Experience supporting manufacturing and/or development activities for active pharmaceutical ingredients, intermediates, or other chemicals.
• Deep technical interest and understanding in Chemical Engineering.
• Familiarity with unit operations such as chemical reactions, distillation, phase separation, filtration, and drying.
• Ability to work well in a team with varied functional relationships and willingness to be a point of accountability.
• Experience with DeltaV, Dynochem, Aspen, and/or electronic lab notebooks.
• Strong analytical and problem-solving skills.
• Strong oral and written communication skills for diverse audiences, including operations staff and management.
• Ability to work independently and as part of a diverse Process Team of management, production, science, and engineering professionals.
• Understanding of process control systems.
• Creativity in identifying improvement opportunities and initiative to implement them.
• Ability to guide or mentor others through processes.
• Flexibility to meet business needs.

Responsibilities

• Perform impact and risk assessments for unit operations.
• Learn the lab and plant design for reactors, including automation recipes and procedures.
• Promote safety and ensure company safety policies are followed.
• Ensure processing equipment complies with internal Quality System requirements, applicable engineering standards, and cGMP requirements.
• Assess rig fit using technical data packages and, as needed, modeling, simulations, or experimental work to verify acceptable heat and mass transfer when scaling processes to the plant.
• Engage and communicate with HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing.
• Author, review, or approve technical reports and regulatory submissions, and ensure records and technical notebooks are adequately maintained.
• Proactively identify quality issues and communicate them appropriately.
• Develop or review plans and timetables for project work.

Benefits

• Company bonus, depending in part on company and individual performance.
• Eligibility to participate in a company-sponsored 401(k).
• Pension.
• Vacation benefits.
• Eligibility for medical, dental, vision, and prescription drug benefits.
• Flexible benefits, including healthcare and/or dependent day care flexible spending accounts.
• Life insurance and death benefits.
• Certain time-off and leave-of-absence benefits.
• Well-being benefits, including an employee assistance program, fitness benefits, and employee clubs and activities.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal