Principal Manufacturing Systems Engineer

Amgen • Cambridge, MA

2d

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Manufacturing Technology and Information Systems Engineer What you will do Let’s do this. Let’s change the world. In this vital role, you will drive overall program success by applying program and project management principles to teams, partnering with business and technology leaders to ensure comprehensive alignment, and finding optimized ways to deliver efficiency and quality for our partners. We are seeking a Principal Manufacturing Systems Engineer with solid leadership skills in any of Amgen Manufacturing locations in the US or Europe to join our Ops Technology Manufacturing & Engineering team to help drive productivity through the company using technology to unlock opportunities to stop, optimize processes and then automate as appropriate. Are you someone that has extensive experience on the Operations technology (Aveva Pi, DeltaV, Rockwell, MES) and Program Management to take progressive project management approaches. Are you eager to take your program management, continuous improvement & SAFE-Agile, financial management skills and use them in creative new ways to build groundbreaking Operation smart technologies that helps develop life-changing biotech medicines?, If so, this may be the right place for you.

Requirements

• Doctorate degree and 2 years of Manufacturing automation/Information systems leadership experience OR Master’s degree and 4 years of Manufacturing automation/Information systems leadership experience OR Bachelor’s degree and 6 years of Manufacturing automation/Information systems leadership experience OR Associate’s degree and 10 years of Manufacturing automation/Information systems leadership experience OR High school diploma / GED and 12 years of Manufacturing automation/Information systems leadership experience

Nice To Haves

• Program and project management and delivery experience around manufacturing core systems like Aveva PI, DeltaV, Rockwell, Korber MES, Digital Infrastructure, and advanced digital smart technologies.
• Solid understanding of GAMP software development lifecycle, ANSI/ISA-S88 and S95 industry standards and methodologies, and 21 CFR Part 11.
• Fluent in Agile methodologies with respect to technology solutions, their development, and timelines.
• Experience as a Product Owner or Scrum Master is a must.
• Manage integration of OT platforms (MES, PI data, etc.) with core manufacturing and enterprise systems (ERP, LIMS, historians, automation layers such as DeltaV and Rockwell, and data platforms).
• Strong written and oral communication skills with scientific domain expertise to communicate effectively with various partners within the organization.
• Self-motivated individual with demonstrated ability to learn new concepts and technologies and work cross-functionally in teams, both internal and external.
• Project finance experience.
• You will have a consultant attitude, with the ability to clarify and control a diverse and shifting program lifecycle.
• Creativity and flexibility will be key components to excelling in this role.

Responsibilities

• Lead large capital project and product teams by fostering Agile delivery while operating within GMP manufacturing environments.
• Partner with site and global stakeholders to prioritize demand, manage backlogs, and balance local needs with global strategy.
• Accountable for financials, resource planning, vendor performance, and delivery against scope, schedule, and quality targets.
• Drive global standards, templates, and best practices for large operations technology project and product design, deployment, lifecycle management, and support to enable scalability and operational excellence.
• Ensure solution delivery meets GMP compliance, data integrity, electronic batch records, and regulatory inspection readiness requirements.
• Lead cross-functional collaboration between site and corporate Operations, Quality, IT, OT, Automation, Platform Owners, and external system integrators.
• Own the global operations technology roadmap, including upgrades, standardization, harmonization, and site deployments, aligned with business and regulatory requirements.
• Mentor and coach junior project managers or Scrum Masters.
• Present status updates and progress to senior leadership at various governance meetings.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: No Education Listed