Principal Investigator, MD

Civia Health•Goodlettsville, TN

About The Position

At Civia Health, we’re reimagining how clinical trials are delivered—by putting patients first and empowering providers to lead innovation. We’re seeking an experienced and compassionate Principal Investigator (PI) to oversee Phase 2–4 clinical trials in a collaborative, mission-driven environment. You’ll play a vital role in ensuring scientific integrity, patient safety, and regulatory compliance while contributing to groundbreaking research. At Civia Health, you're not just taking a job: You're joining a mission to transform the way clinical research is done. Our purpose is bold: to bring clinical trials front and center in your community, make them accessible to everyday people, and empower underrepresented communities to participate. We’re reinventing how clinical studies are run, delivering valid, scalable evidence with a consumer-first mindset. Too often, trials are expensive, fragmented, and overlook the experience of the participant. At Civia, we’re changing that. Our leadership team are experienced industry leading, visionary professionals who know what’s broken — and how to fix it. We treat participants like valued partners, not research subjects. That means supporting their agency, putting their needs, comfort, and enjoyment first — and rewarding them generously for their time and effort. Every team member plays a crucial role in reshaping clinical research. You’ll help make studies more human-centered, inclusive, and efficient. We're looking for people who are driven by purpose, inspired by innovation, and ready to roll up their sleeves to do meaningful work. At Civia, your contributions aren’t just transactional, they’re transformational.

Requirements

Medical degree (MD or DO) with active and unrestricted license.
3+ years of experience as a Principal Investigator in clinical research (Phase 2–4 preferred).
Strong working knowledge of GCP, FDA regulations, and clinical operations.
Excellent leadership, communication, and problem-solving skills.
Passion for innovation, ethics, and patient-centered care.

Nice To Haves

Board certification in internal medicine, endocrinology, or related field preferred.

Responsibilities

Serve as the physician of record and lead clinical oversight for assigned trials.
Review and approve study protocols, informed consent documents, and source documentation.
Conduct physical exams, medical reviews, and oversee safety assessments for participants.
Ensure compliance with all ICH-GCP, FDA, and IRB regulations.
Provide guidance and mentorship to the clinical research team.
Engage with sponsors, monitors, and regulatory bodies as needed.
Occasional travel may be required for audits, site visits, or team meetings.