Principal Investigator / LCMS Scientist (Copy)

RPM ReSearch•Columbia, MO

1d•Onsite

About The Position

We are searching for a Senior / Principal LC-MS Scientist to join a growing bioanalytical team in Columbia, MO. This is a hands-on role within a GLP-regulated environment, supporting bioanalytical studies from method development through reporting. The team is continuing to build, so this role is best suited for someone who is comfortable working independently and taking ownership of their work. This is not a highly structured, task-by-task role. The team is still building, and the right candidate will be someone who can work autonomously, take initiative, and operate effectively without needing day-to-day direction.

Requirements

Bachelor’s degree or higher in Chemistry, Biology, or related field
NO LESS THAN 3+ years of hands-on LC-MS experience (more for Principal level)
Direct experience working in a GLP environment (required)
Strong understanding of method development, validation, and sample analysis
Ability to manage multiple studies and meet timelines
Strong communication skills

Nice To Haves

Experience in a CRO setting
Prior team lead or mentoring experience
Exposure to client-facing work
Experience with Shimadzu, SCIEX, or similar platforms
Experience with Watson or similar systems

Responsibilities

Develop, validate, and execute LC-MS methods for bioanalytical studies
Analyze biological samples (plasma, tissue, etc.) using LC-MS/MS systems
Interpret data and prepare clear, accurate reports for clients
Participate in client communications, including study updates and data discussions
Ensure adherence to GLP standards and regulatory requirements
Review study data and documentation for accuracy and completeness
Troubleshoot technical issues and identify opportunities for improvement
Support instrument calibration, maintenance, and optimization (Shimadzu, SCIEX, or similar)
Collaborate with internal scientific, regulatory, and operational teams