Principal Engineer - Global Reliability Network Lead (Remote)

Amgen • Puerto Rico, TX

6d • Remote

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal Engineer - Global Reliability Network Lead

What you will do
Let’s do this. Let’s change the world! In this vital role, you will lead Amgen’s Global Reliability Network as part of Engineering Operations Services (EOS) department, helping sites turn reliability data, maintenance history, failure trends, and equipment performance insights into actions that improve asset reliability, equipment availability, maintenance effectiveness, and operational capacity. You will also serve as the business lead for the CMMS Asset Performance Monitoring module and reliability-focused equipment insight tools across Amgen’s manufacturing network. Occasional on-site presence at the nearest Amgen operation site may be requested based on business needs.

Requirements

• Doctorate degree & 2 years of engineering industry experience OR Master’s degree & 4 years of engineering industry experience OR Bachelor’s degree & 6 years of engineering industry experience OR Associate’s degree & 10 years of engineering industry experience OR High school diploma/GED & 12 years of engineering industry experience
• Bachelor’s degree in Engineering.
• Experience in maintenance, reliability, engineering, asset management, manufacturing operations, and/or engineering digital transformation.
• Experience leading cross-functional initiatives in site, multi-site, or global environments.
• Strong knowledge of CMMS/EAM and asset performance monitoring systems, such as SAP, Maximo, or equivalent.
• Working knowledge of asset criticality, RCM, FMEA/FMECA, RCA, PM optimization, PdM, condition-based maintenance, and reliability KPIs.
• Ability to translate site needs into scalable business processes, digital product requirements, and improvement actions.
• Strong stakeholder management, communication, network leadership, and change leadership skills.
• Experience with analytics or dashboarding tools such as Power BI, Spotfire, SAP Analytics Cloud, or equivalent.
• Experience in GMP, biopharmaceutical manufacturing, GxP research, laboratory, or other regulated operations.
• Familiarity with ISO 55000, ISO 14224, SMRP, Uptime Elements, or similar reliability and asset management frameworks.
• Certification such as CMRP, CRL, PMP, Lean Six Sigma, or asset management certification.
• Experience deploying predictive maintenance, condition monitoring, smart sensors, AI-enabled analytics, or advanced asset health technologies.
• Experience developing business cases for reliability, maintenance, lifecycle asset management, or capacity improvement projects.
• Fluent English proficiency, written and verbal.
• Availability to commute to the nearest Amgen operation site as business needs arise, including for meetings, training, operational support, or other business-critical activities.

Responsibilities

• Lead the Global Reliability Network Lead a network of site reliability engineers, maintenance leaders, system owners, and technical SMEs.
• Develop and execute the Reliability Network strategy, goals, milestones, and maturity plans.
• Share reliability KPIs, bad actor trends, equipment improvements, lessons learned, and reusable solutions.
• Represent reliability priorities and recommendations in senior engineering governance forums.
• Turn data insights into equipment improvements Use CMMS data, Asset Performance Monitoring, Plant Pulse, PdM findings, and site input to identify recurring failures, high-risk assets, downtime drivers, and bad actors.
• Convert reliability insights into corrective actions, equipment improvements, PM/PdM optimization, spare parts strategies, and capital recommendations.
• Track improvement actions, verify benefits, and scale successful practices across sites.
• Advance asset criticality and maintenance strategy Define and maintain a standard risk-based asset criticality approach across sites.
• Use criticality to prioritize maintenance strategies, work execution, spare parts, lifecycle planning, and performance monitoring.
• Standardize maintenance strategies based on criticality, failure modes, operating context, and performance history.
• Support RCM, FMEA/FMECA, PM optimization, predictive maintenance, and condition-based maintenance approaches.
• Lead Asset Performance Monitoring and PlantPulse adoption Define business requirements for asset health, criticality, failure modes, risk ranking, performance monitoring, and continuous improvement.
• Partner with SAP EAM, Technology/IS, site engineering teams, the Reliability Network, and SMEs to support deployment, training, adoption, and data quality.
• Serve as PlantPulse business owner to ensure tools address reliability pain points, support troubleshooting, and generate actionable equipment insights.
• Connect reliability to business value Partner with OPEX teams to identify reliability improvements that unlock capacity and reduce downtime.
• Translate recurring failures and reliability constraints into business impact.
• Support lifecycle risk visibility for critical assets, including deterioration, obsolescence, maintenance cost, reliability concerns, and end-of-life planning.
• Integrate reliability principles into capital projects from conceptual design through turnover.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree