Principal Electrical Engineering Architect

Seer Inc.•Redwood City, CA

7h•$175,000 - $205,000•Onsite

About The Position

At Seer, we are passionate about empowering our customers to expand scientific discoveries and achieve exceptional scientific outcomes. Our team is growing quickly as we develop innovative approaches to solve complex biological questions. And we believe the next frontier in biology is enabled through a clearer and more complete view of the proteome – something that Seer can uniquely deliver. As we build our team, we are looking for collaborative, driven, intellectually curious people who are committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork, because we believe that this enables the kind of breakthrough thinking that will accelerate our mission. The Role & The Team This role will report to the Director of Systems Integration and join our team based in our Redwood Shores facility. We are seeking a highly skilled Electrical Engineering Architect to lead the electrical design of a next-generation mass spectrometer for life sciences applications. This role requires deep technical expertise in managing the complex electromagnetic environments inherent to charged particle beam instrumentation. You will be responsible for architecting systems that demand extreme precision, stability, and immunity to noise, ensuring optimal ion beam fidelity for advanced analytical workflows, including liquid chromatography-mass spectrometry (LCMS).

Requirements

Master’s degree or Ph.D. in Electrical Engineering, Applied Physics, or a closely related discipline.
Minimum 10+ years of experience in an academic or life-sciences industry laboratory setting (biotech start-up experience preferred).
Demonstrated architectural design experience with mass spectrometers, electron microscopes, focused ion beam systems, particle accelerators or other similar technology.
Proven track record of designs implementing high voltage DC and high amplitude RF electronics.
Extensive practical knowledge of signal integrity, ultra-low noise analog circuit design, and precision timing circuits.
Deep understanding of the physical challenges associated with guiding low-energy ion beams without introducing phase-space distortion.
Strong written and oral communication skills, with demonstrated experience in cross-functional and timely communication.
Strong and collaborative work ethic; must be a self-starter and persistent in achieving objectives to support Seer’s scientific and business goals.
Must work well in a small team setting, with the ability to work independently and collaboratively, while meeting scheduled deadlines in a fast-paced environment

Nice To Haves

biotech start-up experience preferred

Responsibilities

Architect the comprehensive electrical system layout for a novel dual TOF mass spectrometer.
Specify high-voltage DC power supply architecture (up to 15 kV) for precision ion optics and flight tubes.
Develop robust high-voltage RF systems (~1-2 MHz, ~4 kV amplitudes) for ion guides, funnels, quadrupoles, and traps. Ensure high stability and low temperature drift.
Implement rigorous grounding, shielding, and isolation strategies to mitigate RF pickup on lenses and signal lines.
Engineer component-level solutions to minimize electronic noise, voltage ripple, and thermal drift that negatively impact ion beam trajectories, mass resolution, and mass accuracy.
Oversee the integration of high-voltage electronics within high-vacuum systems and define system-level cabling and interconnect strategies.