Principal Cloud & Infrastructure Engineer | Temporary FT & Onsite

Neurocrine Biosciences•San Diego, CA

1d•Onsite

About The Position

The Principal Cloud and Infrastructure Engineer serves as the senior technical authority responsible for designing, modernizing, and optimizing enterprise-scale Azure-centric cloud environments integrated with AWS and on-premises infrastructure. This role drives large-scale platform transformations including workload migration, infrastructure consolidation, automation-first provisioning, cost optimization, GxP-aware cloud environments, and performance engineering across hybrid architectures. The position requires deep expertise in Azure cloud engineering, strong AWS experience, and hands-on integration with VMware virtualization, enterprise storage, identity systems (AD/Azure AD), networking, and scientific compute platforms. The Principal Engineer defines platform strategy, establishes architectural standards, leads complex cross-functional programs, and ensures secure, compliant, highly available, and cost-efficient operations across the enterprise.

Requirements

Bachelor's degree in Computer Science, Information Technology, or related field and 6+ years of infrastructure engineering experience with 4+ years focused on AWS
Master's degree in Computer Science, Information Technology, or related field and 4+ years of experience as listed above
High School Diploma, GED, or equivalent and 10+ years of equivalent experience, training, or certifications
Certifications such as Azure Solutions Architect Expert , Azure DevOps Engineer Expert or similar
Experience supporting GxP-regulated environments
Experience supporting scientific computing / bioinformatics workloads
Experience with container-based platforms (Docker, Kubernetes)
Experience building self-service automation frameworks
FinOps or cloud cost governance experience
Azure Solutions Architect Expert (required)
Understands key business drivers and uses this understanding to accomplish work
Has strong understanding of processes, procedures and systems used to accomplish the work and recognizes downstream impact on other functional areas
Proficient with tools and processes that support work conducted by functional area
Ability to work as part of a team; may train lower levels
Strong communications, problem-solving, analytical thinking skills
Detail oriented yet can see broader picture for department
Ability to meet multiple deadlines, with a high degree of accuracy and efficiency
Strong project management skill

Nice To Haves

AWS Solutions Architect (preferred)

Responsibilities

Lead large-scale technology infrastructure consolidation, virtualization, and cloud migration initiatives.
Drive automation-first engineering using Infrastructure as Code (Terraform, ARM/Bicep, CloudFormation) across cloud and on-prem environments.
Design and implement API-driven, self-service provisioning platforms integrated with ServiceNow and identity systems.
Lead cloud cost optimization and FinOps initiatives across Azure and AWS, including savings strategies and governance controls.
Architect and optimize VMware platforms with high availability, disaster recovery, and footprint reduction strategies.
Design scalable storage architectures across Azure, AWS (S3, FSx), and on-prem NetApp with automated tiering and lifecycle management.
Enable secure, on-demand compute platforms supporting containerized workloads (Docker/Kubernetes) and advanced analytics use cases.
Implement identity-driven access models using AD/Azure AD with policy-based provisioning and role-based controls.
Design and implement hybrid connectivity models including ExpressRoute, VPN, SD-WAN, private endpoints, and secure access solutions.
Integrate security, compliance, and regulatory best practices (including GxP-aware environments) into hybrid architectures.
Build enterprise observability frameworks including performance, reliability, utilization, and cost dashboards to drive operational excellence.