Principal Clinical Scientist, Clinical Development - Hematology

CSL

9d • $168,000 - $199,000 • Hybrid

About The Position

The Principal Clinical Scientist contributes to the scientific development of clinical development programs and individual studies in the Hematology therapeutic area, in alignment with the clinical development plan. The role provides scientific and clinical development input to support the safe, efficient, and timely execution of assigned programs, while ensuring high-quality, compliant outputs.

The position contributes to program and study documents, training materials, medical monitoring oversight, analysis and interpretation of clinical data, and scientific and regulatory publications. It collaborates with internal and external cross-functional stakeholders to translate clinical strategy and protocols into operational deliverables, and supports external study oversight committees. The role may lead development of a Clinical Development Program.

This is a hybrid position requiring at least three days onsite each week. Relocation and mobility assistance are not provided. The expected base salary range at the Waltham, Massachusetts work location is $168,000–$199,000 per year. Total compensation may also include incentive compensation and equity.

Requirements

• PhD, master's degree, or bachelor's degree in a science-related discipline.
• At least 4 years of experience in one or more R&D functions in the biotechnology or pharmaceutical industry for candidates with a PhD; 6 years for candidates with a master's degree; or 8 years for candidates with a bachelor's degree.
• At least 3 years of clinical development research experience.
• In-depth knowledge of pharmaceutical drug development and manufacturing processes, including CMC, non-clinical, clinical, and Regulatory Affairs.
• Ability to work cross-functionally in a matrix environment.
• Excellent oral and written communication skills.
• Strong attention to detail in processes, communications, and documentation.
• Ability to work independently and as part of a team.
• Ability to think creatively and solve problems.
• Experience providing oversight to CROs.

Nice To Haves

• Advanced science-related degree (MSc or PhD).
• PMP certification.

Responsibilities

• Contribute to scientific development of clinical development programs and individual studies in Hematology, aligned with the clinical development plan.
• Provide scientific and clinical development input for safe, efficient, and timely program execution and ensure high-quality, compliant outputs.
• Author or contribute to program- and study-level documents and training materials aligned with scientific strategy, such as clinical development plans, investigator brochures, protocols, eCRFs, informed consent forms, study reference manuals, and investigator training.
• Contribute to development of medical monitoring oversight strategies for clinical studies and implement them to support patient safety oversight and data integrity, including ongoing review of blinded data.
• May lead development of a Clinical Development Program.
• Contribute to authorship and review of manuscripts, conference abstracts, and related materials.
• Collaborate with internal and external cross-functional stakeholders to translate clinical development strategy and protocols into operational deliverables.
• Contribute to scientific analysis and interpretation of clinical data and the preparation of clinical study reports, scientific meeting presentations, peer-reviewed publications, and regulatory submission documents.
• Manage processes and liaise with stakeholders supporting external study oversight committees, including steering committees, independent data monitoring committees, and adjudication committees.

Benefits

• Total compensation may include incentive compensation and equity.
• CSL provides employee benefits; details are available on the company's benefits website.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal