Principal Clinical Database Systems Programmer

BridgeBio Pharma

3d•$172,000 - $188,600•Remote

About The Position

The Principal Clinical Database Systems Programmer performs SAS or SQL data programming to design, build, and maintain clinical data collection systems. The role develops customized data listings, reports, visualizations, and electronic data capture (EDC) study database builds. The programmer manages study-defined specifications and requirements, leads clinical programming activities across one or more studies for Data Management Operations and Clinical Development, and liaises with biostatisticians to understand final requirements and study data/database structures.

Requirements

Bachelor’s degree or equivalent in science and/or a computer systems or IT background.
At least 5–7 years of experience in a pharmaceutical or biotechnology setting.
Advanced programming and analytical skills using SQL, BASE/SAS, SAS/STAT, and SAS macros.
Ability to work independently to create standard datasets, program edit checks, and produce quality data review outputs.
Demonstrated understanding of CDISC and SDTM requirements and implementation guidelines, including the ability to create and validate CDISC standard datasets.
Knowledge of ICH GCP and Good Clinical Data Management guidelines.
Ability to travel less than 10% for visits to BridgeBio headquarters or Biometrics/DM meetings, as required.

Nice To Haves

Advanced technical expertise in databases, EDC platforms such as Medidata Rave or Veeva, data imports and integrations, and data visualization tools such as Tableau or Spotfire.
Python programming language experience.

Responsibilities

Create standard and custom programs and reports using tools such as SAS, Tableau, or other data visualization tools to support data oversight and review.
Lead EDC database build programming, testing, and migration of case report forms, edit checks, and database dynamics using platforms such as Veeva Vault and Medidata Rave.
Collaborate with clients, peers, programmers, project teams, and requestors to clarify and finalize data specifications and respond to evolving project needs.
Support development, delivery, and maintenance of clinical data review standards, tools, and systems across clinical, safety, and operational data sources.
Support Data Management and Clinical Programming initiatives involving clinical data review bridging and database development activities, meetings, and discussions.
Assist with management of electronic data from external sources and vendors for import or integration into clinical database tools, and liaise with vendors on data transfers and specifications.
Assist in reviewing and approving study documentation, including design specifications, user requirements, data transfer specifications, and data standards.
Provide leadership, training, guidance, and support to department members on data review tools and clinical database development.

Benefits

Market-leading compensation
Annual performance bonus
Company equity
401(k) with employer match
Employee Stock Purchase Program (ESPP)
Pre-tax commuter benefits for transit and parking
Referral bonus for hired candidates
Subsidized lunch and parking on in-office days
100% employer-paid medical, dental, and vision premiums for employees and dependents
Health Savings Account with annual employer contributions and Flexible Spending Accounts
Fertility and family-forming benefits
Expanded mental health support, including therapy and coaching resources
Hybrid work model with flexibility
Flexible take-what-you-need paid time off and company-paid holidays
Paid medical and parental leave
Skill development and internal mobility opportunities
Career pathing, continuous education, and professional development programs
Financial rewards, peer-to-peer recognition, and growth opportunities