Principal Associate Scientist, Biology (Contract)

Xaira TherapeuticsSouth San Francisco, CA

About The Position

Xaira Therapeutics is seeking a Principal Associate Scientist to join our Biology & Pharmacology team. This is a hands-on, lab-based role focused on executing in vitro and ex-vivo experiments to support immunology and translational research programs. This position is ideal for someone with strong experience working with immune cell systems and functional assays who enjoys bench work and contributing to data generation in a fast-paced, collaborative environment. You will work closely with scientists across biology and pharmacology to generate high-quality data that supports ongoing discovery efforts.

Requirements

  • B.S. or M.S. in Immunology, Biology, or a related field with 7+ years of relevant industry experience
  • Strong hands-on experience with primary immune cell systems (human and/or mouse)
  • Proven experience executing flow cytometry-based assays
  • Experience with cell-based functional assays (e.g., cytokine assays, proliferation assays)
  • Ability to independently execute experiments and troubleshoot technical issues
  • Strong attention to detail, organization, and record keeping
  • Ability to work effectively in a fast-paced, team-oriented environment

Responsibilities

  • Execute in vitro and ex-vivo experiments to support disease biology, target validation, and therapeutic development
  • Perform immune cell isolation, culture, and functional assays using primary human and/or mouse systems
  • Conduct immune profiling using flow cytometry, including multi-parameter panel execution and analysis
  • Perform functional assays such as T cell activation, proliferation, and cytokine profiling
  • Prepare and process tissue samples, including generating single-cell suspensions for downstream assays
  • Generate, analyze, and clearly document experimental data to support team decision-making
  • Maintain accurate lab records and ensure reproducibility of experimental workflows
  • Collaborate with cross-functional teams to support ongoing research programs

Benefits

  • competitive compensation and benefits package
  • open, flexible, and friendly work environment
  • platform to develop their long-term careers
  • competitive package that includes base salary, bonus, and equity
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