Principal Associate Scientist, Bioanalytical Science
About The Position
Xaira Therapeutics is seeking a Principal Associate Scientist to join our Bioanalytical Sciences team. This is a hands-on, lab-based role focused on developing and executing ligand binding assays to support pharmacokinetic, pharmacodynamic, and target engagement studies across discovery and translational programs. This position is ideal for someone with strong experience in bioanalytical assay development and execution who enjoys bench work and contributing to data generation in a fast-paced, collaborative environment. You will work closely with scientists across biology and pharmacology to generate high-quality data that supports ongoing discovery efforts.
Requirements
- B.S. or M.S. in Biochemistry, Immunology, Analytical Chemistry, or a related field with 7+ years of relevant industry experience
- Strong hands-on experience with ligand binding assay platforms (ELISA, MSD/ECL)
- Proven experience executing flow cytometry-based assays, ideally for receptor occupancy or target engagement
- Experience supporting PK/PD sample analysis across NHP and/or rodent species in a discovery or translational research setting
- Ability to independently execute experiments and troubleshoot technical issues
- Past experience with summarizing data and presenting to internal or external groups.
- Strong attention to detail, organization, and record keeping
- Ability to work effectively in a fast-paced, team-oriented environment
Responsibilities
- Develop, optimize, and execute ligand binding assays (ELISA, MSD/ECL) and flow cytometry-based methods to support PK, PD, receptor occupancy, and target engagement studies for biologic programs
- Support assay development, optimization, qualification, and validation activities for both non-GLP, IND-enabling GLP, and clinical studies
- Contribute to the design and execution of DMPK and bioanalytical studies, generating PK/PD and exposure data to support candidate selection
- Support bioanalytical method development, qualification, and validation for discovery, translational, and clinical programs
- Process and analyze samples across NHP and rodent matrices, including serum, plasma, and tissue
- Generate, analyze, and clearly document experimental data to support team decision-making
- Prepare presentations and data summaries to communicate experimental findings with internal program groups and external CROs.
- Maintain accurate lab records and ensure reproducibility of experimental workflows
- Collaborate with cross-functional teams to support ongoing research programs
Benefits
- competitive compensation and benefits package
- open, flexible, and friendly work environment
- platform to develop their long-term careers
- competitive package that includes base salary, bonus, and equity
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Associate degree
