Principal Analytical Scientist (Automation)

Regeneron Pharmaceuticals•Rensselaer, NY

2d•$92,200 - $150,600•Onsite

About The Position

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Analytical Scientist to join our Quality Control team in Rensselaer, NY, supporting our IOPS organization on-site. In this role, you will shape the future of QC analytical testing by designing, developing, and scaling automated assay workflows across advanced laboratory platforms, while mentoring scientists and fostering a culture of technical growth and innovation. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

8+ years of industry experience in analytical development, laboratory automation, and QC method lifecycle management (or equivalent combination of education and experience).
Demonstrated hands-on expertise in automated liquid handling platforms and associated software programming.
Proficiency in scripting languages (Python, R, or VBA) for data analysis, workflow automation, or system integration.
Deep knowledge of QC analytical techniques including mass spectrometry, chromatography, electrophoresis, bioassay, or ELISA.
Proven ability to work independently, design scientifically sound studies from broad objectives, and drive projects to completion.
Ability to work in a laboratory environment, including standing for extended periods and handling laboratory equipment.
Appropriate gowning and PPE are required in designated areas.

Nice To Haves

PhD in Chemistry, Biochemistry, Biology, or a related field.
Previous experience working in a cGMP or cGLP regulated environment.
Familiarity with Cellario, Venus (Hamilton), or OneLab (Andrew+) automation platforms.
Experience developing and executing technology transfer plans across QC or partner functions.

Responsibilities

Lead the design, implementation, and optimization of automated assay workflows across modern laboratory platforms, applying deep expertise in mass spectrometry, chromatography, bioassay, electrophoresis, and ELISA.
Mentor and develop junior and mid-level scientists, building team capability in analytical science and laboratory automation.
Set priorities, coordinate work, and track progress on analytical and automation initiatives against key milestones.
Independently design and execute studies to evaluate emerging automation technologies and troubleshoot existing systems with limited supervision.
Lead complex investigations into automated method performance, supporting verification activities and driving continuous improvement.
Transfer automated workflows to QC and partner functions by developing training materials, transfer plans, and acceptance criteria.
Engage cross-functional collaborators and equipment vendors to evaluate new technologies and assess their fit for QC applications.
Prepare clear scientific reports, automation procedures, and SOPs; communicate findings, risks, and mitigation strategies to management and cross-functional teams.