Postdoctoral Scientist - Ajami Lab - Department of Neurology
About The Position
The Ajami Laboratory at Cedars-Sinai Medical Center is seeking an outstanding and highly motivated Postdoctoral Fellow to join our growing Neuroimmunology Research Program. The successful candidate will join a vibrant and expanding research program supported by a recently awarded NIH R01 (6th percentile) and an ALS Breakthrough Research Grant from the Milken Institute. These projects investigate how the innate immune system regulates neurodegeneration, with a particular focus on amyotrophic lateral sclerosis (ALS). Using human postmortem tissues, spatial transcriptomics, spatial proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to identify novel therapeutic targets that can be translated into effective immunomodulatory therapies for ALS and other neurodegenerative diseases. This position offers an exceptional opportunity to work at the interface of neuroimmunology, spatial biology, genomics, stem cell biology, and translational neuroscience while contributing to highly collaborative, multidisciplinary research with direct clinical relevance.
Requirements
- Perform routine and sophisticated laboratory procedures.
- Develop, adapt, and implement new research techniques and protocols.
Nice To Haves
- Experience with human postmortem brain and spinal cord tissues
- Experience with spatial transcriptomics
- Experience with spatial proteomics (CODEX)
- Experience with single-cell RNA sequencing
- Experience with human iPSC-derived microglia and motor neuron models
- Experience with CRISPR/Cas9 genome engineering
- Experience with multiomic data integration
- Experience with therapeutic target discovery and validation
- Experience with neuroimmune mechanisms of ALS and other neurodegenerative diseases
Responsibilities
- Designs and performs experiments.
- Maintains experimental records and documentation and analyzes the results with the Principal Investigator.
- Analyzes interpret, summarizes, and compiles data.
- Operates and maintains equipment and instruments.
- May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.
Benefits
- Access to ground breaking technologies, facilities, and resources
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
