Postdoctoral Scholar

Oregon Health & Science University • Portland, OR

1d • Onsite

About The Position

Applications are invited for a Postdoctoral Research position in the laboratory of Dr. Anupriya Agarwal at the OHSU Knight Cancer Institute. The Agarwal laboratory focuses on identifying novel intrinsic and extrinsic signaling pathways that are requisite for leukemia progression, clonal evolution, and drug resistance. The work will focus on discovering the mechanisms of leukemia initiation and drug resistance using multi-omics approaches in murine models and primary human samples for funded projects. The new team member will help lead the project focused on understanding the mechanisms of leukemia initiation and drug resistance. The project will use a variety of advanced molecular biology techniques, CRISPR methods, and flow cytometry analysis, along with single-cell transcriptomic, epigenetic, and genomic profiling in premalignant and malignant models. The candidate is required to have experience in hematology, including functional assays and molecular biology methods, and to work with primary samples using murine models and human samples. A candidate should also be able to perform complex data analysis and downstream analyses using computational approaches. Applicants will need to possess strong technical and organizational skills as well as the ability to manage an independent project. The OHSU Knight Cancer Institute is a pioneer in personalized cancer treatment and research, led by Dr. Brian Druker, whose development of Gleevec transformed Chronic Myeloid Leukemia from a fatal disease to a manageable one and proved that targeted therapies can work. The institute focuses on precision oncology, the early detection, prevention, and treatment of cancer, and creating a welcoming and supportive environment for its caregivers, researchers, and support personnel. Knight affiliates subscribe to three guiding principles: we are bold, we are supportive, and we work as a connected team in our fight to end cancer as we know it. We’d love for you to join us!

Requirements

• PhD
• Minimum of 4 years as a graduate student
• Specialty: Molecular Biology
• In depth knowledge of specific areas of responsibility
• Ability to operate complex scientific equipment
• Passion for science and inquiry
• Ability to synthesize one’s own results and others to formulate hypotheses
• Ability to prioritize multiple tasks at one time
• Must have excellent communication, analytical and organizational skills: both written and verbal
• Ability to work independently and as part of a team
• Experience in hematology, including functional assays and molecular biology methods

Nice To Haves

• PhD degree in Cancer Biology or hematology field
• Prior experience with the analysis of single cell OMICS platform
• Experience with murine models, including xenograft implantation and drug treatments, is preferred
• Experience in performing transcriptomic and epigenetic studies is preferred
• Experience with basic bioinformatics skills is preferred
• 0-2 years of research experience in the relevant field is preferred
• Laboratory experience in hematology or a related field is preferred
• Experience with sequencing library preparation, epigenetics, flow cytometry, or murine disease models would be especially beneficial.

Responsibilities

• Discovering the mechanisms of leukemia initiation and drug resistance using multi-omics approaches in murine models and primary human samples for funded projects.
• Help lead the project focused on understanding the mechanisms of leukemia initiation and drug resistance.
• Use a variety of advanced molecular biology techniques, CRISPR methods, and flow cytometry analysis, along with single-cell transcriptomic, epigenetic, and genomic profiling in premalignant and malignant models.
• Work with primary samples using murine models and human samples.
• Perform complex data analysis and downstream analyses using computational approaches.
• Manage an independent project.

Benefits

• Medical, dental and vision coverage at no or low cost to employees Covered 100% for full-time employees and 88% for dependents
• Several retirement plans to choose from with contributions from OHSU
• 120 hours of vacation time per year
• 96 hours of sick leave a year (prorated for part-time employees)
• Commuter subsidies
• Tuition reimbursement
• Access to group life insurance, disability insurance and other supplemental benefits
• Annual Raises
• Growth/Development Opportunities
• Employee discounts to local and major businesses

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree