Postdoctoral Researcher

University Health Network • Toronto, ON

4d • CA$54,902 - CA$71,372 • Hybrid

About The Position

We are looking for a bioinformatician with demonstrated experience in single-cell RNA sequencing analysis and an interest in incorporating new artificial intelligence tools into the analysis pipeline. The anticipation is that this qualified person will be able to work with large scRNAseq datasets with cell numbers >3,000,000 cells and be able to code in relevant languages to incorporate the latest analysis tools. This is an opportunity to work with state-of-the-art data in the context of novel drugs in early-stage clinical trials. The position will involve industry collaboration with the expectation of academic publication. There will also be internal opportunities for collaboration in our basic research projects focused on HBV pathogenesis using similar samples.

Requirements

• PhD received within 5 years (or MD received within 10 years) in relevant field of study
• Published experience in scRNAseq data analysis
• Interest in human immunology and willingness to learn about hepatitis B infection
• Ability to work independently from home and onsite
• Ability to advise/mentor fellow lab members in bioinformatics analysis strategies
• Problem-solving initiative
• Attention to detail and strong organizational skills
• Good verbal and written communication skills

Responsibilities

• Use/develop pipelines for large, single-cell dataset alignment and quality control.
• Cluster and annotate immune cell populations.
• Use advanced analysis tools beyond basic differential gene expression and pathway analysis.
• Integrate clinical and transcriptomic data for analysis using machine learning and novel artificial intelligence models.
• Effectively visualize and communicate single-cell analysis outputs to bench scientists.
• Mentor graduate students in bioinformatics analysis.
• Organize and maintain datasets on the storage archive.
• Use the UHN high-performance computing cluster.

Benefits

• Competitive offer packages
• Member of the Healthcare of Ontario Pension Plan (HOOPP)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree