Postdoctoral Research Associate - McDonough Lab

Carnegie Mellon UniversityPittsburgh, PA
Onsite

About The Position

The McDonough laboratory in the Department of Chemistry at Carnegie Mellon University is seeking a postdoctoral researcher with high-resolution mass spectrometry (HRMS) experience to work on research projects related to bioaccumulation, biomonitoring, and nontarget analysis (NTA) of emerging organic contaminants. Our research group blends environmental analytical chemistry and chemical biology to study environmental and biological (i.e., toxicokinetics) fate of organic contaminants. Much of our current work centers around characterizing complex commercially- or environmentally-relevant per/polyfluoroalkyl substance (PFAS) mixtures and describing their behavior in living things. The postdoctoral researcher’s projects will focus primarily on assessing bioaccumulation potential and biological transformation of novel PFASs using in vitro tools and HRMS analysis of PFASs using quadrupole time-of-flight mass spectrometry (QTOF-MS) and ion mobility spectrometry (IMS) coupled with liquid chromatography and electrospray ionization (LC-ESI).

Requirements

  • High-resolution mass spectrometry (HRMS) experience.
  • Experience with mass spectrometry, including instrument operation, troubleshooting, and data analysis.

Nice To Haves

  • Experience dividing time among multiple projects.
  • Experience with LC-HRMS and/or GC-HRMS.
  • Experience with independent experimental design and analytical method optimization.
  • Experience training others in laboratory skills and analytical chemistry.
  • Strong writing and communication skills.

Responsibilities

  • Assess bioaccumulation potential and biological transformation of novel PFASs using in vitro tools.
  • Perform HRMS analysis of PFASs using quadrupole time-of-flight mass spectrometry (QTOF-MS) and ion mobility spectrometry (IMS) coupled with liquid chromatography and electrospray ionization (LC-ESI).
  • Contribute to multiple research projects.
  • Operate, troubleshoot, and analyze data from mass spectrometry instruments.
  • Design experiments and optimize analytical methods.
  • Train others in laboratory skills and analytical chemistry.
  • Communicate research findings through writing.
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