Postdoctoral Research Associate - Oncology

St. Jude Children's Research Hospital • Memphis, TN

7d • Onsite

About The Position

We are excited to announce a postdoctoral fellowship in the laboratory of Dr. Lillian Guenther, an Assistant Member in the Division of Molecular Oncology at St. Jude Children’s Research Hospital in Memphis, TN. Dr. Guenther’s research specifically focuses on identification and investigation into the biology of novel therapeutic targets in pediatric bone sarcomas. Dr. Guenther’s research utilizes genome-scale CRISPR screening and other complementary large-scale chemical and genomic screening modalities, as well as advanced molecular biology and biochemical techniques in multiple types of pre-clinical models to uncover novel dependencies, or tumor-specific genes critical for tumor initiation or survival. Research in the Guenther laboratory is designed to discover how such critical dependencies enable cell growth, with a focus on mechanistic investigation and opportunities for eventual clinical translation. An area of advanced research and interest in the lab is investigating proteins critical for DNA damage repair in bone tumors, alternative lengthening of telomeres (ALT) biology, as well as novel tumor suppressor/predisposition factors in osteosarcomas. The Guenther Lab seeks a post-doctoral research associate with a passion for cancer biology, with interests in rigorous mechanistic investigation of novel oncogenes and tumor suppressors that impact pediatric bone sarcoma tumorigenesis. We seek a candidate with interest and willingness to work with genetically engineered mouse models (GEMMs), immunocompromised/xenograft mouse models, as well as in vitro systems to unravel intricate biological mechanisms in a critical and thoughtful manner.

Requirements

• PhD in a biological sciences discipline
• Exceptional writing and presentation skills
• Track record of academic productivity

Nice To Haves

• Specific interests and experience in DNA damage repair, replication stress, or ALT biology
• Experience working with GEMMs

Responsibilities

• Project leadership
• Writing manuscripts
• Contributions to grant applications
• Applying to fellowship grants as eligible
• Mentorship and supervision of more junior trainees in the lab

Benefits

• Generous yearly Professional Development Allowance for travel to scientific meetings
• Support from the St. Jude Post-Doctoral Association for career advancement, scientific writing and speaking seminars, and community-building events.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree