About The Position

The Research Department at New England Biolabs invites applications for a Postdoctoral Fellow to conduct research on nucleases. The fellow will use in vitro biochemistry and structural biology to characterize the mechanisms and substrate specificity of known nucleases and discover new enzymes through genome mining and functional screening. The position suits candidates with strong scientific communication skills and an interest in both basic and applied research. The role offers broad research training, collaboration with academic and industrial institutions, opportunities to publish in peer-reviewed journals, and participation in national and international conferences. The estimated base salary is $74,000; salary decisions depend on factors including individual qualifications, job location, internal equity, and market data alignment.

Requirements

  • Ph.D. in Biochemistry, Chemistry, Molecular Biology, or a related discipline.
  • Excellent verbal and written communication skills.
  • Publication of original scientific work in high-quality journals.
  • Ability to work independently and collaboratively.

Nice To Haves

  • Experience in biochemical and structural characterization of nucleic acid enzymes.
  • Technical expertise in enzymology, including kinetics.
  • Experience with enzyme superfamily studies, including genome mining, phylogenetic tree analysis, and ancestral sequence reconstruction.
  • Submitting a cover letter with the application is highly encouraged.

Responsibilities

  • Design and execute experiments to characterize exonuclease and endonuclease biochemistry, including enzyme kinetics and NGS-based assays.
  • Create high-throughput activity assays for enzyme discovery.
  • Communicate discoveries and findings to the scientific community through publications and presentations.
  • Collaborate with internal and external colleagues.
  • Maintain high standards of scientific rigor, data quality, and documentation.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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