UNIV - Postdoctoral Fellow in Cerebrovascular Pathophysiology - Department of Pathology and Laboratory Medicine

Medical University of South Carolina•Charleston, SC

12d•Onsite

About The Position

The Department of Pathology and Laboratory Medicine at the Medical University of South Carolina (MUSC) is seeking a highly motivated and talented postdoctoral researcher to join our team part-time. This position focuses on investigating the role of neurovascular unit dysfunction in brain aging and Alzheimer’s Disease and Related Dementias (ADRD) pathogenesis. The successful candidate will leverage a systems biology approach and cutting-edge technologies—including cellular and molecular biology techniques, single-cell RNA sequencing, spatial proteomics, RNAscope, neuropathology, super-resolution confocal microscopy, and ADRD animal models—to investigate how the neurovascular unit changes in preclinical models.

Requirements

Ph.D. in neurobiology, molecular cell biology, neuroscience, or other related fields.
Ability to work independently in experimental design and project execution.
Good oral and written communication skills.
Ability to train and supervise technicians and graduate students.
Ability to obtain and maintain a valid drivers license.
Computer literacy.
Ability to learn and use new processes, tools and equipment as required.

Nice To Haves

Previous experience with AD transgenic models, snRNA-seq, spatial proteomics, and confocal microscopy is highly preferred.

Responsibilities

In consultation with the PI, design and execute experiments to advance independent research projects.
Perform specific assays including histological procedures, quantitative RT-PCR, immunoblotting, immunofluorescence, confocal microscopy, and flow cytometry assays.
Conduct standard animal experiments, including handling transgenic mice and rats, intraperitoneal and tail vein injections, rodent general surgeries, collecting animal brain tissues, IHC, and data analysis.
Assist the PI in training and supervising graduate students, technicians, research assistants and junior lab members.
Attend seminars, career development activities locally and nationally at conferences, submit abstracts and present data at local, national & international meetings.