Postdoctoral Associate, Bathe Lab
About The Position
The Postdoctoral Associate will work on PRISM (Probe-based Imaging for Sequential Multiplexing), a multimodal synaptomics platform developed in the lab. This platform simultaneously measures synaptic protein composition, local mRNA translation, and synaptic activity at single-synapse resolution. This role offers an exciting opportunity to contribute to answering fundamental questions about how neuropsychiatric diseases such as schizophrenia and autism manifest at the synapse in human neurons, and whether those changes can be pharmacologically reversed. The postdoc will play a central role in extending PRISM into human iPSC-derived neurons for scalable, automated drug screening. The position sits at the intersection of technology development, translational neuroscience, and drug discovery.
Requirements
- Ph.D. in biomedical engineering, cell biology, molecular biology, or a related field.
- Experience with mammalian cell culture.
- Experience with multiplexed protein or RNA detection methods.
- Experience with quantitative data or image analysis.
Nice To Haves
- Experience with high-content imaging.
- Experience with automated screening platforms.
- Experience with computational image analysis pipelines.
Responsibilities
- Extending PRISM into human iPSC-derived neurons for scalable, automated drug screening.
- Neuronal cell culture.
- Multiplexed imaging assay development.
- Automation of liquid-handling and imaging workflows.
- Computational analysis of high-content synaptic datasets.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
