Post-Doctorate Research Associate - Lipidomics and Biomarker Development

Pacific Northwest National LaboratoryRichland, WA
Onsite

About The Position

Pacific Northwest National Laboratory (PNNL) is a world-class research institution powered by a highly educated, diverse workforce committed to collaboration and work–life balance. Every year, scores of dynamic, driven post-docs come to PNNL to work with world-renowned researchers on cutting edge science, innovations, and technologies. The Translation Omics Group at PNNL is seeking a Postdoctoral Research Associate to join our multi-disciplinary team with a focus on mass spectrometry-based lipidomics analysis and LC-MS biomarker development related to type 1 diabetes. The postdoc will be working across multiple cutting-edge NIH-funded projects related to biomedical and clinical applications. The individual will develop and optimize targeted and untargeted LC-MS methods to advance lipidomics profiling capabilities, identify and validate candidate biomarkers, and contribute to type 1 diabetes research. The candidate will have the opportunity to receive technical training in the latest cutting-edge mass spectrometry applications available within PNNL. The selected candidate is expected to: Have strong expertise in mass spectrometry analytical approaches for omics and biological interpretation, Develop and validate quantitative LC-MS assays for candidate biomarkers in complex biological matrices (e.g., plasma, serum), Conduct independent research and work on team assignments, lead manuscripts and maintain a strong overall publication record in the peer-reviewed scientific literature, Interact, communicate, and problem-solve with a diverse team of multi-disciplinary research staff across PNNL, Present research projects at national conferences, Work safely and independently in a laboratory setting, and Participate in the development of research proposals. An ideal candidate will also have experience in ion mobility spectrometry and bioinformatics pipelines. This is a full-time, limited-term employment position. The duration of this appointment is two years, with the option of extending the appointment for up to three years.

Requirements

  • Have strong expertise in mass spectrometry analytical approaches for omics and biological interpretation
  • Candidates must have received a PhD within the past five years (60 months) or within the next 8 months from an accredited college or university.
  • The ideal candidate would have a Ph.D. degree in analytical chemistry, biochemistry, or closely related fields with strong biological knowledge of human metabolism.
  • Experience with mass spectrometry.
  • Experience with chromatography (LC-MS) and/or ion mobility spectrometry, and the ability to tackle large, complex omics datasets is desirable but not required.
  • Additionally, the candidate should be safety-oriented, possess excellent communication skills (oral and written), be collaborative, and have a desire to learn and develop new concepts and research techniques.
  • The ability to critically think, problem-solve, and execute routine research tasks independently is essential.

Nice To Haves

  • Experience in ion mobility spectrometry and bioinformatics pipelines.

Responsibilities

  • Develop and validate quantitative LC-MS assays for candidate biomarkers in complex biological matrices (e.g., plasma, serum)
  • Conduct independent research and work on team assignments, lead manuscripts and maintain a strong overall publication record in the peer-reviewed scientific literature
  • Interact, communicate, and problem-solve with a diverse team of multi-disciplinary research staff across PNNL
  • Present research projects at national conferences
  • Work safely and independently in a laboratory setting
  • Participate in the development of research proposals

Benefits

  • health insurance
  • flexible work schedules
  • medical insurance
  • dental insurance
  • vision insurance
  • telehealth care options
  • mental health benefits
  • wellness coaching
  • health savings account
  • flexible spending accounts
  • basic life insurance
  • disability insurance
  • employee assistance program
  • business travel insurance
  • tuition assistance
  • relocation
  • backup childcare
  • legal benefits
  • supplemental parental bonding leave
  • surrogacy and adoption assistance
  • fertility support
  • company-funded pension plan
  • 401 (k) savings plan with company match
  • vacation hours
  • paid holidays
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