Post-Doctoral Scientist - Technical Services and Manufacturing Science

Eli Lilly and Company • Us, IN

3d • Onsite

About The Position

Post-Doctoral Scientists at Lilly are responsible for ensuring the reliability of manufacturing systems, searching for and implementing continuous improvements, driving technical projects, maintaining processes in compliance with regulations, and designing and developing drug processes and delivery systems. This specific position is within the Technical Services/Manufacturing Science (TS/MS) organization and will provide technical and scientific support for the development of commercial processes (synthesis and purification) for biomolecules including proteins, peptides, and oligonucleotides. The role involves designing and executing experiments to advance process knowledge, process optimization, and production technical transfer. Scientists contribute to the TS/MS organization and participate in cross-functional teams, gaining a comprehensive understanding of the pharmaceutical industry, Good Manufacturing Practices (GMP), and regulatory requirements.

Requirements

• Ph.D. in scientific disciplines of Biochemistry, Biology, Molecular Biology, Pharmacology, Chemistry or related fields.
• Demonstrated experience and proficiency in the areas of protein, oligonucleotide, and peptide chemistry and/or purification.
• Requires a record of publication in peer reviewed journals and presentations / posters at scientific conferences.
• Qualified applicants must be authorized to work in the United States on a full-time basis.
• Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Responsibilities

• Ensuring reliability of our manufacturing systems
• Searching for and implementing continuous improvements
• Driving technical projects
• Maintaining our processes in a state of compliance with US and global regulations
• Designing and developing drug processes and delivery systems
• Designing and executing experiments to advance process knowledge, process optimization and production technical transfer
• Understanding the scientific principles required for manufacturing intermediates, drug substances and drug products, including the interaction of chemistry and equipment.
• Understand the chemistry and stability of small molecules, peptides and/or biomolecules.
• Develop appropriate laboratory-scale models for key process steps in synthesis and/or purification of biomolecules.
• Design, conduct, and analyze statistically-designed experiments to deepen process understanding and optimize processing conditions.
• Understand scale-up requirements and, as needed, partner with the pilot plant to conduct appropriate scale-up work.
• Provide technical support for process development areas if needed.
• Strong technical writing and documentation of all work in an appropriate manner.
• Mentor lab associates to enhance their technical capabilities.
• Participate in technology transfer as needed.
• Ability to work well independently and collaboratively.

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree