Post Doctoral Scholar-Comprehensive Cancer Center

The Ohio State University

3d • Onsite

About The Position

The Postdoctoral Scholar will conduct independent and collaborative research within the laboratory of Dr. Hassane Zarour at the OSUCCC – James Pelotonia Institute for Immuno-Oncology (PIIO). The position will focus on basic and translational cancer immunology research aimed at understanding mechanisms of response and resistance to cancer immunotherapy, immune checkpoint blockade, and tumor microenvironment-mediated immune dysfunction. The Postdoctoral Scholar will design and execute mechanistic studies utilizing patient-derived samples, advanced immune profiling technologies, molecular biology approaches, and preclinical models to advance novel immunotherapeutic strategies and biomarkers for cancer treatment. The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation's largest public universities. The OSUCCC – James Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body's immune system to fight cancer at all levels, from prevention to treatment and survivorship. Trainees benefit from an enriching educational environment led by world-renowned mentors in cancer immunotherapy, complemented by a robust seminar series, access to top-tier research facilities, and a dynamic culture of innovation that drives transformative discoveries in cancer care.

Requirements

• PhD, MD/PhD, or equivalent doctoral degree in Immunology, Cancer Biology, Molecular Biology, Cell Biology, Biomedical Sciences, Oncology, or a related biomedical science field.
• Experience conducting independent scientific research in cancer biology, immunology, translational medicine, or a related discipline.
• Demonstrated expertise in cellular and molecular biology techniques.
• Experience with flow cytometry, immune profiling, molecular analyses, and experimental design.
• Strong analytical, scientific writing, communication, and data interpretation skills.
• Ability to work effectively in multidisciplinary and collaborative research environments.

Nice To Haves

• Experience in cancer immunology, tumor immunology, immune checkpoint biology, or immunotherapy research.
• Experience with multiparameter flow cytometry, tumor-infiltrating lymphocyte analyses, and immune monitoring technologies.
• Experience with multiplex immunohistochemistry, spatial biology, tissue imaging, and quantitative image analysis platforms.
• Experience with animal models of cancer, including tumor implantation, tissue collection, and surgical procedures.
• Experience with molecular biology techniques including cell culture, PCR, immunoblotting, ELISA, viral vector systems, and genetic manipulation approaches.
• Record of peer-reviewed publications and scientific presentations.
• Experience mentoring students, trainees, or laboratory personnel.

Responsibilities

• Conduct independent and collaborative research within the laboratory of Dr. Hassane Zarour at the OSUCCC – James Pelotonia Institute for Immuno-Oncology (PIIO).
• Focus on basic and translational cancer immunology research aimed at understanding mechanisms of response and resistance to cancer immunotherapy, immune checkpoint blockade, and tumor microenvironment-mediated immune dysfunction.
• Design and execute mechanistic studies utilizing patient-derived samples, advanced immune profiling technologies, molecular biology approaches, and preclinical models to advance novel immunotherapeutic strategies and biomarkers for cancer treatment.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree