Post-Doctoral Research Fellow

Fred Hutchinson Cancer Center • Seattle, WA

1d • Onsite

About The Position

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Ring Lab of Synthetic and Systems Immunopharmacology is located within the Translational Science and Therapeutics Division and is a member of the Immunotherapy Integrated Research Center (IIRC). Their primary focus is on developing unique and first-in-class therapeutic drugs for cancer immunotherapy using cutting-edge protein engineering with directed evolution. The lab has developed therapeutics that are currently in clinical trials, such as ST-067 (a "decoy-resistant" IL-18), MDNA-11 (CD122-biased IL-2), and ALX-148/evorpacept (an ultra-high affinity SΙRPα decoy). Moreover, the Ring Lab is actively working on developing platforms for identifying new targets in cancer immunotherapy. These technologies include the REAP platform for discovering autoantibodies in patient samples, and high-throughput techniques in synthetic antibody engineering and proteogenomics to pinpoint new tumor antigens.

Requirements

• MD or PhD in a related field
• Broad experience in molecular and cell biology methods and the ability to master new techniques and approaches
• Excellent verbal and written communication skills
• A team player with strong aptitude for collaboration

Nice To Haves

• Experience in one or more of the following areas: Cancer biology, Immunology, CAR-T, Systems biology/bioinformatics
• Experience with mouse models is desirable

Responsibilities

• Conduct research to decode the autoantibody reactome in a range of disease states using REAP technology.
• Design and execute antibody characterization assays through biochemical and biophysical approaches.
• Work collaboratively within the Ring lab as well as with other groups at Fred Hutch and external collaborators.
• Prepare manuscripts for publication.
• Present research findings at group meetings and scientific conferences.
• Stay current with relevant publications.
• Provide mentorship to postbaccalaureate and graduate students.
• Assist with weekly lab maintenance.
• Other duties as assigned.

Benefits

• medical/vision
• dental
• flexible spending accounts
• life
• disability
• retirement
• family life support
• employee assistance program
• onsite health clinic
• income-based child care subsidy
• tuition reimbursement
• paid vacation (22 days per year)
• paid sick leave (up to 30 calendar days per occurrence of a qualifying reason)
• paid holidays (13 days per year)
• paid parental leave (up to 4 weeks)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree