Post-Doctoral Research Fellow -Autoantibodies

Fred Hutchinson Cancer Center • Seattle, WA

2d • Onsite

About The Position

Fred Hutchinson Cancer Center is seeking a Post-Doctoral Research Fellow to join the Lampe and Lastwika labs. This role focuses on translating autoantibodies produced by B lymphocytes into tumor diagnostic and therapeutic agents. The labs integrate state-of-the-art methods from biochemistry, cellular and molecular biology, and immunology to isolate tumor-specific autoantibodies directly from cancer patients. A major focus is studying how B cells and their autoantibodies recognize and target tumor antigens. The work has demonstrated that tumor-specific autoantibodies can be excellent biomarkers of lung tumorigenesis and can be detected prior to diagnosis. The approach involves capturing autoantibodies bound to their native tumor-derived epitopes ex vivo, showing they target posttranslational modifications with high specificity. The goal is to translate these findings into antibody-based theranostic applications. Projects may involve lung cancer early detection assays, immunoPET imaging, and antibody-based therapeutics. The work utilizes human samples and techniques including immunofluorescence microscopy, western blotting, immunohistochemistry, molecular engineering, flow cytometry, and microarray piezoelectric printing.

Requirements

• A recent Ph.D. in a relevant field
• Knowledge and experience in cancer biology, biochemistry, or immunology
• Track record of productive research
• Ability to work independently and collaboratively in a team
• Excellent communication and organizational skills

Responsibilities

• Involved in all aspects of research, from experimental design to manuscript preparation and publication.
• Develop creative approaches to experimental design.
• Work independently and collaboratively in a team.
• Contribute to a supportive and inclusive research environment.

Benefits

• Medical/vision
• Dental
• Flexible spending accounts
• Life insurance
• Disability insurance
• Retirement plan
• Family life support
• Employee assistance program
• Onsite health clinic
• Income-based child care subsidy
• Tuition reimbursement
• Paid vacation (22 days per year)
• Paid sick leave (up to 30 calendar days per occurrence of a qualifying reason)
• Paid holidays (13 days per year)
• Paid parental leave (up to 4 weeks)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree