Post-Doc Research Associate

UNC-Chapel HillChapel Hill, NC
Onsite

About The Position

The Department of Pharmacology at the University of North Carolina at Chapel Hill is seeking a Postdoctoral Research Associate to investigate the molecular and structural mechanisms that regulate G protein-coupled receptor (GPCR) signaling pathways in the laboratory of Dr. Henrik Dohlman. The successful candidate will leverage expertise in structural biology, cryo-electron microscopy (cryo-EM), protein biochemistry, and cell signaling to characterize receptor complexes, G protein signaling networks, kinase-mediated regulatory mechanisms, and downstream signaling events. Research efforts will focus on understanding the molecular basis of GPCR and G protein regulation, including mechanisms of signal desensitization, allosteric communication, and disease-associated signaling dysfunction, with the goal of advancing our understanding of signal transduction processes relevant to human health and disease.

Requirements

  • Demonstrated expertise in molecular and cellular biology research methodologies.
  • Record of scientific productivity through publications, presentations, or other scholarly accomplishments.

Nice To Haves

  • Experience in GPCR signaling, receptor regulation, or cell signaling research.
  • Expertise in cryo-EM, protein biochemistry, and molecular biology techniques.
  • Strong record of scientific productivity, including publications and presentations.
  • Excellent communication, organizational, and collaborative skills.
  • Experience mentoring undergraduate and graduate trainees.

Responsibilities

  • Investigate molecular and structural mechanisms regulating G protein-coupled receptor (GPCR) signaling pathways.
  • Characterize receptor complexes, G protein signaling networks, kinase-mediated regulatory mechanisms, and downstream signaling events using expertise in structural biology, cryo-EM, protein biochemistry, and cell signaling.
  • Focus research on understanding the molecular basis of GPCR and G protein regulation, including mechanisms of signal desensitization, allosteric communication, and disease-associated signaling dysfunction.
  • Advance understanding of signal transduction processes relevant to human health and disease.
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