Physician Scientist, Cardiometabolic Genetics

Regeneron Pharmaceuticals•Cambridge, MA

5d•Onsite

About The Position

Physician Scientist, Cardiometabolic Therapeutic Area Genetics Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Physician Scientist to join our Cardiometabolic Therapeutic Area Genetics (TAG) team at the Regeneron Genetics Center (RGC). In this role, you will use massive-scale human exome sequencing to discover and validate new therapeutic targets in obesity and obesity-associated metabolic disease, accelerating therapeutic development through new human genetics and epidemiological insights, while collaborating with RGC teams and Regeneron's pre-clinical and clinical development teams. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

An MD with a strong background in and knowledge of human genetics and genetic epidemiology
Proficiency with R or similar software, and familiarity with high-performance computing environments
Experience integrating different data resources to translate initial genetic findings, and familiarity with meta-analysis of genome-wide summary statistics

Nice To Haves

An MD/PhD with training in translational human genetics, genetic epidemiology, or a related discipline is preferred
Experience as an investigator in Randomized Controlled Trials
Experience in the clinical management or medical research of cardiometabolic disease

Responsibilities

Generate key research questions, then design and execute studies and analyses to address them
Interpret study results and summarize insights across formats — documents, presentations, patent applications, and publications — for different audiences
Leverage RGC and Regeneron datasets, external resources, and the scientific/medical literature to address research questions, weighing quantitative and qualitative strength of evidence
Support target nomination and validation by applying RGC's human genetics capabilities alongside Regeneron's therapeutics platforms and development modalities
Partner with Clinical Development to evaluate clinical-stage programs and identify opportunities for human genetics studies that inform indication selection or safety evaluation
Participate in the intellectual life of the Cardiometabolic TAG, RGC, and Regeneron at large, helping build an inclusive culture where everyone can perform at their best
Represent the Therapeutic Area Genetics team in cross-functional initiatives across RGC and Regeneron