Pharmacy 340B Program Manager

Mass General Brigham•Boston, MA

2d•$99,466 - $141,804•Hybrid

About The Position

The 340B Program Manager serves as a key subject-matter expert, partnering cross-functionally with Pharmacy, Finance, and IT to ensure program integrity, optimize performance, and maximize financial impact across the enterprise. The Pharmacy 340B Program Manager is vital to the team and responsible for managing registration and participation in the 340B Program for all 340B covered entities and ensuring that all use of 340B throughout the organization is fully compliant. The 340B Program is a critical component of our mission—enabling continued investment in patient care, research, and services for vulnerable populations. In this role, you’ll have enterprise-wide visibility and impact, contributing to strategic planning and governance initiatives that shape the future of care delivery.

Requirements

Deep expertise in the 340B Drug Pricing Program
Strong analytical and problem-solving skills with the ability to translate data into actionable insights
Experience working in complex, large-scale health systems
Proven ability to collaborate across multidisciplinary teams and influence stakeholders
Doctor of Pharmacy Pharmacy/Pharmaceutical Studies required
Pharmacy Managed Care Experience 5-7 years required
Medicaid Experience 2-3 years required
Strong knowledge of 340B, supply chain, and pharmacy regulatory requirements (DPH, BORP, TJC, CMS, FDA, USP)
Experience with health system supply chain operations and integrated EHR platforms (e.g., Epic, Cerner)
Knowledge of hospital pharmacy systems and workflows
Strong analytical thinking and problem-solving skills
Effective written and verbal communication skills
Ability to lead teams, manage priorities, and perform under pressure
Proven ability to drive accountability and meet deadlines
Excellent verbal and written communication skills.
Excellent organizational and time management abilities.
Effective interpersonal skills, including the ability to effect collaborative alliances, promote teamwork and ensure a high degree of internal and external customer satisfaction.
Ability to work as a team player or autonomously with strong organizational skills, project management skills and attention to detail.
Ability to work with vendors and other departments to keep multiple tasks on track and bring projects successfully to completion.

Nice To Haves

Licensed or eligible for licensure to practice pharmacy in the Commonwealth of Massachusetts preferred

Responsibilities

Lead and oversee all aspects of the 340B program, including audit readiness, compliance, and regulatory adherence
Drive split-billing operations, data analytics, and enterprise-level reporting to ensure accuracy and maximize savings
Develop and implement policies, procedures, and best practices to strengthen program performance
Monitor and optimize contract pharmacy relationships and performance
Present insights and recommendations to senior leadership across Pharmacy, Finance, and Compliance
Maintains knowledge and expertise on Section 340B rulings and related interpretations, including new and proposed regulations, current trends and issues.
Assesses potential organizational impact of 340B changes and ensures 340B program is continuously compliant with federal regulations.
Develops and/or updates 340B policies and procedures whenever there is clarification to interpretation, or change in the rules, regulations, or guidelines to 340B requirements.
Reviews 340B policies and procedures annually.
Shares expertise and provides training, education, and communication to staff and Program participants regarding 340B Program compliance.