Operations Manager - Center for Therapeutic Genetics

Broad Institute•Cambridge, MA

1d•$104,000 - $145,333•Hybrid

About The Position

The Center for Therapeutic Genetics (CTG) is a collaborative nonprofit effort pioneering a new model for rare genetic disease treatment by developing reusable platform infrastructure for gene-editing therapies. This "genetic surgery" model aims to extend care to millions of rare disease patients. CTG is a tri-institutional effort between the Broad Institute, The Jackson Laboratory’s Rare Disease Translational Center (JAX-RDTC), and Boston Children’s Hospital (BCH), with the Broad serving as the administrative hub. This role, as a Broad employee reporting to the CTG Director, will coordinate day-to-day program operations and cross-institutional workflows. The Operations Manager will be crucial in linking CTG strategy to execution, ensuring complex initiatives are coordinated, enabling smooth execution towards CTG goals, maintaining budgets and timelines, supporting alliances, and developing scalable processes. The ideal candidate will have demonstrated independent judgment, strong workflow management, and the ability to coordinate across multiple teams and institutions. While hands-on scientific experience is not required, intellectual versatility to understand therapeutic translation and business/operational acumen are essential for advancing CTG's sustainability and building operational excellence.

Requirements

5+ years of progressive experience in project management, alliance management, scientific operations, or a related field.
A bachelor’s degree is required.
Must possess the intellectual versatility to understand and communicate scientific and therapeutic translational ideas.
Proven track record of managing complex projects, timelines, and budgets.
Ability to balance big-picture strategic thinking with meticulous attention to executional details.
High emotional intelligence and analytical acumen (balancing EQ & IQ); capable of building trust and consensus among diverse groups of stakeholders.
A strong bias toward action, initiative, and problem-solving, coupled with a hands-on, "roll-up-your-sleeves" work ethic.
Exceptional written and verbal communication skills, with ability to translate complex ideas into clear, actionable, and professional formats.

Nice To Haves

Experience working in multi-institutional partnerships is preferred.
A master's is preferred.
A background in science, medicine, or a related field is highly preferred.

Responsibilities

Provide comprehensive operational and logistical support for the operational systems, workflows, and structures of CTG necessary for executing on CTG’s mission and goals, including governance, strategy, communication, finance, and overall operations.
Work closely with CTG leadership and partners to maintain and execute against strategic goals and priorities, as well as maintain division of responsibilities and compliance with institutional policy.
Manage and track the CTG operations budget, ensuring optimal allocation of resources for internal CTG staff and seconded institutional staff and reporting to fiscal sponsors and partner institutions.
Work with scientific project managers and staff to understand scientific programs and their associated milestones, budgets, and timelines to support the Director and Program Leads (Preclinical, Technical, and Clinical) in keeping initiatives on track.
Contribute to iterating formal strategic documents, including business plans, executive summaries, and presentation decks, and ensure they are properly organized and accessible to relevant parties.
Coordinate logistics, materials, and follow-up for CTG Board of Directors, Council of Partners, and Scientific Advisory Board meetings, ensuring governance-level decisions are documented and communicated to program teams.
Partner with the Preclinical, Technical, and Clinical Leads to ensure program-level governance gates (e.g., go/no-go reviews) are scheduled, resourced, and properly escalated to the Governance Committee.
Support CTG leadership in refining and maintaining existing infrastructure and governance models with founding partners (JAX-RDTC and BCH) as well as external partnerships and stakeholders.
Navigate and manage complex, multi-stakeholder relationships, serving as a highly effective alliance manager, including supporting key operational tri-institutional meetings and administrative working group discussions, following up on action items.
Act as the primary operational partner to collaborating organizations, demonstrating strong initiative and consistent follow-through.
Collaborate with leadership to identify, engage, and onboard new partners and resources.
Work closely with the Office of Sponsored Research and CTG leadership to maintain financial oversight, including budget development and monitoring, subaward management, sponsor reporting, and effort tracking across CTG’s funding sources.
Serve as a standing member of the CTG Financial Oversight Committee, working closely with representatives of partner institutions as well as fiscal sponsors to provide support for high-level financial governance matters for CTG.