About The Position

The Nurse Practitioner (NP) or Physician Assistant (PA) provides acute evaluation and management for adult Medical Oncology and Hematology patients with early or advanced solid tumors and hematologic malignancies. Care includes symptom management, oncologic emergencies, and treatment-related adverse events, including immunotherapy-related toxicities. Providers work closely with patients’ primary oncology and hematology teams to coordinate care across the continuum. The role rotates among three Acute Care Clinic areas—Cancer Treatment Unit coverage, REACH intervention rooms, and outpatient acute care visits—and the Immunotherapy (ICI) Toxicity Clinic. The Acute Cancer Care Clinic aims to reduce emergency department visits through direct admissions and outpatient management with close follow-up, and to support shorter hospital stays through follow-up care for hospitalized cancer patients. The role also supports remote management nursing teams caring for patients with neutropenic fevers and respiratory illness, and may contribute to expanding remote patient monitoring programs. Providers triage acutely ill patients in the cancer treatment unit and support nurses managing patient calls. The new REACH intervention space enables IV interventions on the oncology floor, such as fluids and electrolytes. In the Cancer Infusion Therapy Center, the provider assesses and manages patients receiving systemic cancer therapy. Duties include responding to infusion reactions, evaluating acute cancer-related concerns during treatment visits, coordinating urgent diagnostic workups and interventions, and collaborating with infusion nursing staff, pharmacists, and the primary oncology team. In the ICI Toxicity Clinic, the provider evaluates and manages patients with toxicities ranging from mild to emergent. Follow-up may consist of a single visit or continue for weeks to months, depending on patient needs. Clinic coverage also includes the ICI service pager, providing collaborative support to outpatient and inpatient colleagues with questions about ICI toxicities. Acute and ICI clinic coverage is rotated among providers; pager coverage for the two clinics is assigned to different NPs or PAs working that day. The stated goal is to have four NPs or PAs working each day to cover the clinics. This autonomous role has collaborative support as needed and requires coordination with patients’ primary cancer care teams and multidisciplinary partners, including Infectious Diseases, Gastroenterology, Interventional Radiology, Pulmonary Medicine, Palliative Care, Emergency Medicine, and other hospital-based services. The practice is fast-paced and evolving, with initiatives to develop enhanced observation capabilities for real-time interventions, improve patient access, and prevent escalation of care when possible. Providers may partner with clinical and operational leadership to shape workflows, expand services, and advance patient-centered oncology care across Mayo Clinic’s three shields.

Requirements

  • For the NP pathway: a master’s-prepared graduate of an accredited school of nursing and Nurse Practitioner program.
  • For the NP pathway: current Minnesota RN license and certification, or eligibility for certification, as an FNP, ANP, or ACNP; certification must be obtained within six months of employment.
  • For the PA pathway: graduation from an accredited Physician Assistant program, current PA certification by NCCPA, and registration as a PA by the Minnesota Board of Medical Practice, or eligibility for registration.
  • Must be eligible for DEA registration and billing privileges.
  • External and internal applicants must attach two to three letters of reference to the online application.
  • New graduates must upload three letters of reference from preceptors who can attest to their clinical abilities.
  • Mayo Clinic employees applying must attach their three most recent performance evaluations to the online application.
  • Successful candidates should have a solid foundation in internal medicine and strong communication, critical-thinking, adaptability, and time-management skills.
  • A passion for oncology care and interest in continuous learning, quality improvement, and program development.

Responsibilities

  • Provide acute evaluation and management for adult Medical Oncology and Hematology patients with solid tumors or hematologic malignancies.
  • Manage symptoms, oncologic emergencies, and treatment-related adverse events, including immunotherapy-related toxicities.
  • Rotate coverage among the Cancer Treatment Unit, REACH intervention rooms, outpatient acute care visits, and the ICI Toxicity Clinic.
  • Facilitate direct admissions and manage patients in outpatient settings with close follow-up when appropriate to help reduce emergency department visits.
  • Provide follow-up care for hospitalized cancer patients to support shortened hospital stays.
  • Support remote management nursing teams caring for cancer patients with neutropenic fevers and respiratory illness.
  • Provide triage support for acutely ill patients in the cancer treatment unit and for nurses managing patient calls.
  • Assess and manage patients receiving systemic cancer therapy in the Cancer Infusion Therapy Center.
  • Respond to infusion reactions and evaluate acute cancer-related concerns arising during treatment visits.
  • Coordinate urgent diagnostic workups and interventions and collaborate with infusion nursing staff, pharmacists, and primary oncology teams.
  • Evaluate and manage ICI toxicities in outpatient settings, providing follow-up according to patient needs.
  • Cover the ICI service pager and provide collaborative support to outpatient and inpatient colleagues regarding ICI toxicities.
  • Collaborate with primary cancer care teams and multidisciplinary partners to coordinate patient care.
  • Contribute to the development of enhanced observation capabilities, remote patient monitoring programs, workflows, and services as the practice evolves.
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