mRNA process development scientist

Serova•San Francisco, CA
•Onsite

About The Position

Serova builds personalized cancer vaccines. Each vaccine is made for the individual patient from their own samples and given in partnership with their treating physician. Every batch we make is for one patient, and we're building a GMP manufacturing facility with Twist to make them. The role: Every batch we make is for one patient. You'll make and QC our mRNA and LNPs, and build the process and QC pipelines that let us make each vaccine quickly and reliably. You'll also help carry that process into the GMP facility we're building with Twist.

Requirements

  • PhD, or 3+ years in industry, working on RNA or nucleic acid therapeutics
  • Hands-on with IVT, purification, LNP formulation and QC
  • Based in the San Francisco Bay Area, or willing to relocate
  • Authorized to work in the US, or a realistic path to get there

Nice To Haves

  • High-throughput QC: experience building QC pipelines for RNA and DNA using NGS, capillary electrophoresis or LC-MS
  • RNA-LNP production at a biotechnology company
  • RNA chemistry: modifications, capping, conjugation
  • Liquid handling and automation
  • Experience writing Python for analysis
  • Tech transfer into GMP, or work with CDMOs

Responsibilities

  • Make and QC mRNA and LNPs
  • Build process and QC pipelines for vaccine production
  • Carry process into the GMP facility

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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