Molecule Steward Lead - Small Molecules

GSK•Boston, PA

1d•Hybrid

About The Position

You will lead molecule stewardship for small molecule programs across development and manufacturing. You will partner with discovery, process development, analytics, regulatory, manufacturing and external suppliers. We value collaborative leaders who make clear technical decisions, care for quality, and focus on patient impact. This role offers visible influence across program lifecycles, strong growth opportunities, and the chance to help GSK unite science, technology and talent to get ahead of disease together. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Lead technical stewardship for a portfolio of small molecule programs from candidate selection through commercial lifecycle. Define and maintain product control strategies, lifecycle plans and technical deliverables. Coordinate cross-functional teams on technology transfers, process performance qualification, and ongoing process verification. Oversee technical risk assessments and deliver mitigation plans for quality, supply and regulatory readiness. Provide hands-on technical leadership for investigations, troubleshooting and major change programs across sites and suppliers. Mentor and develop the molecule stewardship team and build strong relationships across the network.

Requirements

Bachelor’s degree in chemistry, pharmaceutical sciences, chemical engineering or related field.
At least 8 years’ experience in small molecule development, analytical development, process development or related area.
Demonstrated experience in molecule stewardship, technology transfer or product lifecycle management for small molecules.
Experience leading cross-functional teams and making technical decisions in a matrix environment.
Knowledge of global regulatory expectations for pharmaceutical development, manufacturing and quality.
Experience managing technical aspects of investigations, deviations and corrective actions.

Nice To Haves

Master’s or PhD in a relevant discipline.
Direct experience with technology transfer to multiple sites and with contract manufacturing organizations.
Experience designing stability programs and analytical characterization strategies for small molecules.
Familiarity with risk-based approaches and project management tools.
Proven track record developing technical talent and leading diverse teams.
Comfortable working across time zones and with cross-cultural, matrixed teams.

Responsibilities

Own end-to-end technical strategy and decision points for assigned small molecule assets.
Translate scientific and analytical data into clear, actionable guidance for program teams and stakeholders.
Ensure data integrity, documentation and evidence support for regulatory submissions and inspections.
Drive alignment across sites, contract manufacturers and internal teams to ensure consistent product performance.
Lead Product Technical Lifecycle Team activities and yearly robustness reviews to identify and resolve risks.
Share best practices for characterization, stability strategies and analytical approaches to improve product robustness.