MES Technical Lead / Systems Architect LP2

Lilly • Lebanon, IN

11d • $129,000 - $211,200 • Onsite

About The Position

Lilly is building a new gene therapy manufacturing site (LP2) in Lebanon, Indiana. This role owns the Manufacturing Execution System (MES) end-to-end — from the Tulip application layer and Tulip Table data model, through MuleSoft integrations connecting SAP, QbDVision, and LabVantag, to the MQTT-based Unified Namespace driving real-time equipment communication. You will serve as both the technical authority over the platform’s architecture and the hands-on engineer responsible for its ongoing design, build, and validation.

Requirements

• Bachelor's degree in IT, Software/Computer Engineering or related field
• 5+ years with MES or pharma manufacturing IT platforms, including system integration (middleware/ERP/PLM) and Computer System Validation (CSV) in GMP settings
• Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Nice To Haves

• Modern software architecture and integration patterns
• MuleSoft/Anypoint, DataWeave for MES–ERP(SAP)–PLM integrations
• MQTT, Unified Namespace (UNS), OPC UA knowledge
• CSV experience: Validation/Test Plans, IQ/OQ/UAT, design specs under 21 CFR Part 11/ALCOA+
• Understanding of eBRs, non-terminal record controls, e-signatures
• Git/GitHub, GitHub Actions, MUnit, ALM/Jira
• Familiarity with MABL and ServiceNow
• Strong cross-functional communication and problem-solving skills

Responsibilities

• Serve as Technical Lead/SME for LP2 MES architecture, design standards, and technical direction
• Design, build, and validate Tulip applications for GxP manufacturing workflows and electronic batch records
• Direct automation integrations with Automation Engineering (equipment commands, confirmations, process value subscriptions)
• Author/approve design specs ensuring compliance with ALCOA+ and 21 CFR Part 11
• Guide components through validated migration lifecycle (DEV → QA → Production)
• Participate in Change Control Board (CCB) and ServiceNow change management
• Partner with Manufacturing Operations, Automation Engineering, and Quality (BQA/CSQA)
• Mentor MES engineers; act as escalation point for complex issues
• Collaborate with MES Product Owner on ALM requirements/backlog
• Report system status and technical risk to site/IT leadership

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level