Medical Director
About The Position
Flatiron Health is seeking a data- and technology-oriented clinician with oncology expertise and a passion for using real-world evidence (RWE) to accelerate progress against cancer. The Medical Director will join the Global Research Oncology team, which operates across the US, UK, Germany, and Japan, and collaborate with clinicians, data scientists, epidemiologists, software engineers, product managers, account directors, and clinical data specialists to develop, commercialize, and deliver oncology research data and services, including solutions leveraging artificial intelligence. The role is a core medical resource focused particularly on precision medicine and cancer genomics, helping biopharma clients apply clinical and molecular use cases across the R&D lifecycle, from early pipeline discovery through post-market clinical development. The position serves as a clinical oncology and precision medicine expert, supporting high-volume custom data requests across cancer types, including rare tumors and complex multi-omic biomarker profiles. It partners with clients on translational oncology and discovery, clinical development translation, and pre-sales scoping; applies clinical-molecular frameworks to custom client requests and data deliveries; develops internal training and documentation; and contributes physician expertise to research projects and scientific presentations. The role is remote, with working hours aligned to the team. Candidates may be considered at Associate Medical Director or Medical Director level based on experience and scope of prior precision medicine ownership.
Requirements
- MD or equivalent, with foundational training in oncology, hematology, or a related subspecialty.
- Post-training clinical, academic, or early industry experience; qualifying experience is counted after completion of a subspecialty fellowship.
- For Associate Medical Director level: 1–3 years of qualifying post-fellowship experience.
- For Medical Director level: 3–5+ years of qualifying post-fellowship experience.
- Direct experience with cancer genomics.
- Familiarity with clinical trial design, protocol development, or early-phase (Phase I/II) clinical development.
- Deep clinical intuition and comfort learning about diverse, low-incidence rare tumors and complex molecular landscapes.
- Ability to collaborate in a matrix-structured environment with multiple stakeholders and product lines and translate technical medical and genomic concepts for non-clinical teams.
- Ability to manage concurrent tasks, contribute to intermediate-complexity clinical data projects with senior-leader guidance and mentorship, and meet ongoing deadlines in a fast-paced, technology-driven environment.
- Leadership, problem-solving, analytical, and communication skills, including the ability to multitask and prioritize.
Nice To Haves
- Exposure to laboratory translational oncology, cancer genomics, or biomarker discovery research.
Responsibilities
- Serve as a core medical expert for custom data requests across oncologic diseases, including rare tumor types and complex multi-omic biomarker profiles.
- Scope, design, and clinically validate custom datasets and analyses for biopharma partners, flexibly working across disease areas.
- Partner with clients early in the R&D lifecycle to use clinical-molecular datasets for target discovery, characterization of biomarker-defined cohorts, evaluation of tumor biology, and combination therapy approaches.
- Help researchers validate preclinical hypotheses in real-world cohorts and explore clinical trial findings through reverse translation.
- Apply clinical development and trial design principles to help clients bridge traditional clinical endpoints and real-world evidence.
- Help clients assess how real-world data may support external control arms, historic cohorts, or synthetic control designs for niche or rare trial populations.
- Provide clinical and molecular data expertise during pre-sales, client scoping, and solution building, using internal or off-the-shelf external AI tools.
- Translate client clinical development planning, target validation, and complex inclusion and exclusion criteria into precise data specifications across data assets.
- Partner with matrixed project teams to apply clinical-molecular frameworks to complex dataset deliveries and custom client requests.
- Support development of internal training resources and clinical documentation about rare biomarker cohorts and molecular data structures.
- Contribute physician expertise to research study projects, with support from senior leaders, including presenting or speaking at scientific conferences.
Benefits
- Flexible work hours and flexible paid time off.
- Comprehensive compensation package.
- 401(k) contribution.
- One-to-one financial advice and other financial health resources.
- Mental well-being tools and services.
- Parental benefits and policies, including family-building care and generous leave.
- Fertility, adoption, and surrogacy support through path-to-parenthood programs.
- Travel support for safe healthcare services.
- Bonus and equity eligibility.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
