Medical Director, Immunology

Sanofi • Cambridge, MA

1d • $178,500 - $257,833 • Hybrid

About The Position

The Medical Director, U.S. Immunology serves as the product expert and strategic medical leader for Sanofi’s U.S. Immunology portfolio. The role develops and executes an integrated, above-indication medical and scientific strategy, including evidence generation and scientific information exchange with key stakeholders. It partners closely with Medical Field, Clinical, Commercial, Regulatory, Market Access, global teams, alliance management, and other U.S. cross-functional partners to tailor plans to local needs and resources. Externally, the Medical Director supports healthcare professionals and payers in optimizing patient care and treatment outcomes through evidence-based decisions.

The role oversees U.S. medical planning across medical education, communications and publications, health outcomes, safety, and Phase IIIB–IV clinical research, including annual budget management. It supports clinical research and real-world evidence generation, scientific engagement, compliant medical review, and the use of AI and advanced analytics to inform medical strategy. The position represents Sanofi at scientific meetings and builds relationships with experts in the therapeutic area.

The role is based in Cambridge, Massachusetts, or Morristown, New Jersey, and requires the ability to travel up to 35% of the time. The listed salary range is $178,500.00–$257,833.33; compensation is determined based on demonstrated experience. Employees may be eligible for company benefit programs.

Requirements

• Advanced Practice Provider with at least 5 years of relevant clinical experience in allergy/immunology, or an advanced degree as an NP or PA, or at least 5 years of Medical Affairs experience in allergy/immunology; the posting describes these qualifications as strongly preferred.
• Strong knowledge of healthcare systems, the evolving medical landscape, regulatory and payer environments, public health, and industry trends.
• Sound scientific and clinical judgment, including an in-depth understanding of the scientific method and clinical applications.
• Ability to understand and communicate scientific and medical data to internal and external stakeholders.
• Effective internal and external stakeholder management, cross-functional collaboration, and ability to influence decision-making without authority in a complex, matrixed environment.
• Strong leadership presence and ability to represent Medical Affairs across the company and with leaders at all levels.
• Excellent written, oral, and presentation communication skills.
• Strong interpersonal, analytical, problem-solving, time-management, and project-management skills; ability to prioritize and manage expectations in a complex environment.
• High personal integrity and commitment to ethics and scientific standards.
• Knowledge of pharmacovigilance and local regulatory processes.
• Digital literacy.
• Ability to travel up to 35% of the time to customers, external meetings, trainings, and internal meetings.

Nice To Haves

• Industry experience in Medical Affairs and/or Clinical Development.
• Significant experience in Medical Affairs launch and life-cycle management activities.
• Track record of developing and executing U.S. medical strategies.
• Experience in clinical-trial design and execution.
• Ability to turn innovative strategies into actionable plans while remaining pragmatic and focused on priorities.
• Strategic thinking informed by business practices, industry and medical practice, and company objectives.
• Comfort with ambiguity and ability to adapt with agility.
• Understanding and success in working across different cultures.
• Proven change-management record and a change-champion mindset.
• Commitment to lifelong learning.

Responsibilities

• Develop and execute an integrated U.S. Medical Plan covering Medical Education, Medical Communications and Publications, Health Outcomes, Safety, and Phase IIIB–IV clinical research and Investigator Sponsored Trials, including annual budget management.
• Translate medical strategy into tactical plans and communicate progress to leadership, the Core Team, and execution partners.
• Align medical strategy with clinical development and commercial objectives and adapt it to local U.S. needs.
• Provide medical leadership and scientific input to Clinical, Commercial, Market Access, Regulatory, and Sales for marketed products and pipeline assets.
• Partner with Field Medical, HEVA, Market Access, Marketing, Legal, and Regulatory to maintain scientific accuracy and strategic alignment.
• Collaborate with health economics colleagues to address evidence gaps and payer-relevant data needs.
• Manage high-level external stakeholder relationships with Field Medical leadership and contribute to medical engagement planning and budget oversight.
• Support U.S. Phase IIIB–IV clinical programs, including protocol development, case report forms, statistical analysis plans, and timely study-data reporting.
• Oversee clinical studies in compliance with GCP/ICH guidelines and company standards.
• Review and approve Investigator Sponsored Trial concepts and protocols under applicable SOPs.
• Identify post-marketing clinical trial and registry needs and oversee their management and execution.
• Ensure company- and investigator-sponsored trial data are publicly disclosed in a timely, accurate, and balanced manner.
• Identify research collaboration opportunities to address key clinical questions in the therapeutic area.
• Apply AI and advanced analytics to medical strategy, including evidence synthesis, signal detection, and identification of unmet medical needs.
• Guide the medical team in evaluating and adopting AI approaches for literature analysis, clinical data interpretation, and scientific communication.
• Oversee design, generation, and integration of Real World Evidence studies into the U.S. medical plan; ensure findings are accurately communicated and incorporated into medical strategy and publications planning.
• Build and maintain relationships with Key Opinion Leaders, researchers, and clinical experts.
• Lead medical and scientific advisory boards and represent Sanofi at medical congresses, advisory boards, and scientific meetings.
• Provide disease-state and product training to internal and external audiences.
• Review and approve promotional and medical materials in compliance with corporate standards and applicable regulations and codes.
• Review and approve Regulatory, Safety, Scientific Affairs, and Commercial materials for scientific accuracy.
• Review applications for independent medical education grants and review training materials for medical and commercial employees.
• Partner with U.S. Drug Safety on clinical-trial adverse-event management, post-marketing safety surveillance, and safety-signal communication.
• Identify and escalate Product Alerts to the Core Team in coordination with Drug Safety, USRAMP, and Global Medical Affairs.

Benefits

• Health and wellbeing benefits, including healthcare, prevention, and wellness programs.
• At least 14 weeks of gender-neutral parental leave.
• Employees may be eligible to participate in company employee benefit programs.
• Rewards package recognizing employee contributions.

What This Job Offers

• Job Type: Full-time
• Career Level: Director