Medical Director, Clinical Development

Kelonia Therapeutics•Boston, MA

1d•Onsite

About The Position

At Kelonia Therapeutics, our ambitions are bold: to dramatically expand the benefit and reach of genetic medicines. Our goal is to change what’s possible for genetic medicine by building the capabilities, experience, and commitment to bring life-saving medicine to every patient in need. We are a human-first company, driven by a mission to develop transformative genetic medicines for patients and their loved ones. We have brought together pioneers in cell and gene therapy, guided by extraordinary scientific founders and a team committed to turning breakthrough science into real-world impact. As we grow, we are building a culture that values rigor, collaboration, and care for one another. As a Medical Director in the Clinical Development group, you will support day-to-day medical monitoring, clinical development, data services, and pharmacovigilance for lead programs, as well as future indications. This isn't just a job; it's an opportunity to contribute to groundbreaking therapies, to be part of a company's inception, and to make a transformative impact on patients' lives. If you're passionate about scaling a company from the ground up, making a real difference, and shaping the inclusive culture we're proud of, this opportunity is tailor-made for you. Join us and be a driving force in achieving excellence in viral engineering. This position is well-suited for an early-career MD—including individuals transitioning from academia or with limited industry experience—who want to learn, build, and take meaningful ownership of a clinical programs from day one.

Requirements

MD required with training in oncology, hematology, or a related field.
Open to candidates directly from academia or with early industry experience (industry experience preferred but not required)
Strong interest in oncology drug development, particularly in cell and gene therapy
Foundational understanding of clinical trial design, safety evaluation, and data interpretation
Interest and willingness to learn and contribute to clinical documentation, including protocols, IBs, and regulatory materials
Ability to analyze clinical data and communicate insights clearly
Collaborative, low-ego mindset with a willingness to be hands-on and learn in a fast-paced environment

Responsibilities

Support clinical development activities across 1–2 oncology programs, including supporting our lead clinical program KLN-1010, with the ability to expand scope over time
Perform ongoing medical review of clinical data, including safety, efficacy, and patient-level insights
Contribute to and progressively lead key clinical deliverables, including: Clinical study protocols and amendments, Investigator’s Brochures, Clinical study reports and medical summaries, Regulatory submission documents (e.g., INDs, briefing materials)
Partner closely with Clinical Operations, Regulatory, Biometrics, and Translational teams to support high-quality study execution
Participate in medical monitoring and safety review activities
Support regulatory submissions and interactions, including preparation of FDA-facing materials, and pharmacovigilance reporting
Engage with investigators and clinical sites to support trial conduct and enrollment
Contribute to clinical strategy discussions, with increasing ownership as experience grow