Medical Director MD Immunology

Neurocrine Biosciences • San Diego, CA

5d • Hybrid

About The Position

Neurocrine Biosciences is a leading biopharmaceutical company dedicated to discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. The company has a robust pipeline, including compounds in mid- to late-phase clinical development. Neurocrine Biosciences is building the next chapter of its clinical development portfolio and is seeking a Medical Director, Clinical Development – Immunology to help advance promising research-stage molecules toward and through early clinical development. This role offers an opportunity for a Medical Director who enjoys being close to the science and the study, translating emerging biology into thoughtful clinical research strategies, designing studies that answer important development questions, and working collaboratively with colleagues across various disciplines.

Requirements

• MD or DO degree with accredited residency training and board certification in a relevant clinical specialty for the therapeutic area.
• 2+ years of experience in clinical research and development (Phase 1–4) in either a pharmaceutical/biotechnology company or a clinical research/academic environment, or related experience.
• Clinical expertise in gastroenterology, dermatology, or another specialty relevant to immune-mediated disease.
• Experience serving as a Medical Monitor and/or Study Lead for industry-sponsored clinical trials.
• Demonstrated experience designing clinical studies and developing protocols, including selection of endpoints, eligibility criteria, dose strategy, and other key design elements.
• Experience in early clinical development, including translating preclinical or translational findings into clinical hypotheses and development plans.
• Experience working on Phase 2 or Phase 3 studies in immune-mediated diseases.
• Experience interpreting emerging efficacy, safety, biomarker, and pharmacology data to inform study-level decisions.
• Working knowledge of global drug-development requirements, Good Clinical Practice, and regulatory expectations for investigational therapies.
• Experience contributing to regulatory documents and interacting with health authorities.
• Experience engaging investigators, key external experts, CROs, and other external partners.
• Strong understanding of the competitive and evolving treatment landscape within gastroenterology, dermatology, or Immunology more broadly.
• The ability to influence and lead cross-functional teams without relying on direct reporting authority.

Responsibilities

• Serve as a key physician and study-level clinical leader for assigned Immunology development programs.
• Independently lead clinical studies while contributing medical and scientific expertise to broader development strategy.
• Lead the design, development, and execution of Phase 1–3 clinical studies, working closely with multidisciplinary development teams.
• Develop and implement clinical study protocols and contribute to the clinical research strategy for assigned programs.
• Serve as a Sponsor Medical Monitor, providing medical oversight throughout study conduct and making study-level medical and safety decisions.
• Partner with Drug Safety colleagues to assess adverse events, evaluate emerging safety information, and support ongoing benefit-risk assessment.
• Work closely with Clinical Operations to oversee study execution in accordance with Good Clinical Practice, applicable regulations, and company procedures.
• Analyze and interpret clinical data and translate findings into clear scientific and development insights.
• Contribute to clinical study reports, investigator brochures, regulatory documents, and other materials supporting clinical development and regulatory interactions.
• Partner with Clinical Pharmacology, Biometrics, Translational Medicine, and Research colleagues to incorporate biomarkers and translational endpoints into development plans where appropriate.
• Identify and engage clinical investigators, consultants, and external experts and build productive relationships with leaders in the Immunology community.
• Bring an informed understanding of the evolving treatment landscape, standards of care, competitor activity, and emerging science to study-level development decisions.
• Collaborate across Research, Product Development, Business Development, Medical Affairs, and other functions to evaluate development opportunities and inform clinical research plans.
• Communicate study progress, emerging data, risks, and recommendations clearly to development teams and senior leaders.

Benefits

• Retirement savings plan (with company match)
• Paid vacation, holiday and personal days
• Paid caregiver/parental and medical leave
• Health benefits to include medical, prescription drug, dental and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree