Material Science Principal Scientific Associate (Contract)

Atrium Works•Boston, MA

About The Position

The Material Science Principal Scientific Association will support Vertex's drug development through proficiency in a range of related technical processes and procedures. The role will perform a range of materials science and engineering activities to advance drug candidates from early clinical development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools.

Requirements

Master's degree in chemical or materials engineering or related materials science/chemistry/physical science
Bachelors Degree (or equivalent degree) in a related physical science sciences and 5+ years of relevant employment experience
Typically requires 0 - 3 years experience with a Master's degree in chemical or materials engineering or related materials science or the equivalent combination of education and experience with other degree levels
Sound knowledge of pharmaceutical and engineering principles required for solid dosage form development including impact of material properties resulting from blending, granulation, and compression and Quality by Design (QbD) approach
Hands on experience with formulation techniques, processing equipment, and unit operations at both the laboratory and clinical manufacturing scales.
Strong math skills applying statistical analysis and general engineering principles
Effective communicator (written and verbal) with ability to present findings in a team setting including ability to explain why procedures or approaches are being used
Strong interpersonal skills with a clear ability to work with a team/matrix environment
The ability to work in a fast-paced environment, manage priorities, and maintain timelines for multiple projects
Detail-oriented

Responsibilities

Demonstrate proficiency with advanced characterization techniques and develop predictive models which connect material properties to pharmaceutical processing conditions
Help design, plan, and execute laboratory experiments that assist in drug characterization and formulation development of solid dosage forms with minimal supervision and within project timelines
Interpret data to form sound conclusions by performing basic statistical analysis of experimental data
Maintain accurate and complete laboratory notebook capturing protocols, results and observations
Document integrated experimental outcomes in presentations and research reports in a timely manner
Comply with all relevant Safety and GMP procedures
Participate in department/group discussions