Manufacturing Technician 4 - Rotating Shift

Merck•Saint Louis, MO

4d•Onsite

About The Position

Join our St. Louis Cherokee facility at MilliporeSigma, a leading contract development and manufacturing organization (CDMO) and a recognized Center of Excellence for antibody-drug conjugate (ADC) manufacturing. We are seeking passionate and enthusiastic professionals to contribute to our innovative bioconjugate production, leveraging over 35 years of expertise in the field. As a vital part of our dedicated team, you will play a key role in delivering high-quality ADCs that improve the quality of life for patients suffering from cancer and other debilitating diseases. With our state-of-the-art technologies and commitment to excellence, you will ensure the highest standards of quality and compliance in our ADC manufacturing processes. As a Manufacturing Technician 4 – Rotating Shift, you will be expected to safely execute tasks, develop new approaches, and perform support operations in a cGMP regulated environment for the support of API (Active Pharmaceutical Ingredients) manufacturing teams, including maintaining equipment, preparation of solutions, staging of equipment and supplies, and other various manufacturing support activities.

Requirements

Associate Degree in Biology, Chemistry, or other life science discipline OR High school diploma or GED.
1 + years’ experience in a pharmaceutical GMP operations environment (Manufacturing, Quality, MSAT, Buffers).

Nice To Haves

Experience with Antibody Drug Conjugates (ADCs), including knowledge of their formulation and manufacturing processes.
Prior experience in an API manufacturing environment.
Strong mechanical aptitude.
Experience in Good Distribution Practices (GDP)
Demonstrated process improvement experience.
Familiarity with FDA, EMA, and other regulatory standards.
Demonstrated knowledge and experience in various computer skills, including Windows (Word, Excel, PowerPoint, etc.)

Responsibilities

Prepare buffer formulations for Drug Substance manufacturing, ensuring safety and quality, while maintaining cleanliness in the manufacturing area.
Perform routine processes, including buffer formulation, ultrafiltration, and chromatography.
Maintain equipment, prepare reagents, and stock materials.
Clean production equipment and spaces used in the manufacturing process.
Execute daily tasks following cGMPs and quality-approved procedures, documenting all activities in compliance with GDP standards.
Dispose of cleaning and process waste safely, maintain supply stock levels using the Kanban system.
Ensure compliance with Safety and Quality guidelines by adhering to procedures, conducting safety inspections, performing preventive maintenance, and assisting with quality deviations.
Support departmental operations by training new employees, assisting with daily functions, and contributing to process improvement, safety, quality, and 6S initiatives in collaboration with the department supervisor.