Manufacturing Supervisor – Downstream Bioprocessing (Night Shift)

Elanco•Elwood, KS

10d•Onsite

About The Position

The Manufacturing Supervisor – Downstream Bioprocessing is responsible for leading manufacturing personnel and daily operations supporting the bulk production of monoclonal antibody (mAb) products at Elanco's Elwood, Kansas manufacturing site. This role oversees production activities across downstream bioproprocessing operations, ensuring production targets are achieved while maintaining the highest standards of safety, quality, regulatory compliance, and Good Manufacturing Practices (cGMP). The supervisor also plays a key role in developing team members, driving operational excellence, and fostering a culture of accountability and continuous improvement.

Requirements

Highschool diploma or equivalent
3+ years experience in a regulated, commercial manufacturing environment.
Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas.

Nice To Haves

Bachelor’s degree in biomanufacturing related field
Biomanufacturing experience
Monoclonal antibody manufacturing
Understanding of USDA, FDA, EU GMP, cGMP regulatory standards
Operational excellence, lean manufacturing, six sigma, TPS experience
Demonstrated success in leadership
Experience with SAP, OSI PI, VEEVA

Responsibilities

Lead and oversee daily manufacturing operations supporting downstream bioprocessing activities, including buffer formulation, cell clarification, protein A chromatography, and Tangential Flow Filtration, while partnering with upstream and fill/finish and ensuring adherence to production schedules.
Supervise, coach, and develop manufacturing personnel through performance management, training, and regular feedback to build a high-performing, engaged team.
Ensure manufacturing activities are performed in compliance with USDA, EMA, and cGMP requirements, approved procedures, and batch production records.
Maintain a strong presence on the production floor to promote safe work practices, operational excellence, and a culture of quality and accountability.
Coordinate with Quality, Engineering, Maintenance, Validation, Supply Chain, and other cross-functional teams to support compliant and efficient manufacturing operations.
Monitor production performance, equipment readiness, and schedule adherence while ensuring timely completion of batch records, SAP transactions, and manufacturing documentation.
Lead or support investigations, root cause analyses, and corrective and preventive actions (CAPA) for operational events, deviations, and equipment or process issues.
Drive continuous improvement initiatives that enhance manufacturing efficiency, strengthen compliance, and improve overall operational performance.