Manufacturing Senior Manager, Liso-cel CAR-T, Manufacturing Operations
About The Position
At Bristol Myers Squibb, our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team. The Senior Manager, Manufacturing provides oversight of Manufacturing Managers and Work Centered Teams operating on a 24/7 schedule to execute Cell Therapy manufacturing processes while sustaining a culture of safety, compliance, accountability, innovation, urgency, passion, and continuous improvement. This role reports to the Manufacturing Associate Director.
Requirements
- Bachelor’s degree in a related field preferred, or equivalent work experience; advanced degree preferred.
- 7+ years of relevant manufacturing experience, including at least 5 years of leadership experience managing direct reports.
- Extensive knowledge of EHS, cGMPs, biotechnology principles, manufacturing systems, lean manufacturing, and regulated operations; Green Belt certification preferred.
- Strong communication, adaptability, strategic leadership, team selection, and people management skills.
Nice To Haves
- Green Belt certification preferred.
Responsibilities
- Ensure Manufacturing Managers and WCT members execute Cell Therapy manufacturing in compliance with cGMPs, approved SOPs, WIs, batch records, safety expectations, and ALCOA+ documentation principles.
- Maintain hands-on process expertise across unit operations, support MRB data collection, provide weekend/technical coverage as needed, and develop CAR-T manufacturing and regulatory knowledge.
- Manage production resources by tracking availability, supporting scheduling needs, maintaining records of planned/unplanned absences, and hiring talent aligned with job requirements, budget, and BMS values.
- Set priorities, establish WCT goals, monitor performance, and report metrics and progress through Tier meetings, performance reviews, site control plans, and cross-functional manufacturing forums.
- Maintain 100% on-time training compliance, ensure personnel are qualified before performing tasks, allocate time for training, and disqualify personnel from GMP tasks when compliance gaps are observed.
- Build and develop high-performing teams through recruiting, onboarding, Workday profile maintenance, performance management, recognition, coaching, regular 1:1s, career development, and timely feedback.
- Lead deviation troubleshooting and quality record ownership as BPO/BTA, ensure clear and timely deviation entries, monitor metrics, identify repeat causes, drive on-time closure, and prevent recurrence through continuous improvement.
- Participate in CAPAs, Change Controls, and projects; define or own actions for Manufacturing and ensure implementation before due dates.
- Control expenses within area of influence, including overtime, supplies, and travel/expense costs.
- Model leader behaviors by maintaining shopfloor presence, conducting Gemba/Go & See activities, using tiered management, visual management, coaching kata, root-cause problem solving, risk escalation, and cross-functional collaboration.
Benefits
- wellbeing support
- retirement and financial protection benefits
- insurance offerings (medical, dental, vision, life and disability)
- Flexible Time Off (FTO)
- 11 paid company holidays each year
- 160 hours of paid vacation annually for new hires
- 3 optional holidays
- paid sick leave
- up to two paid volunteer days per year
- summer hours flexibility
- leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
- annual Global Shutdown between Christmas Day and New Year's Day
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What This Job Offers
Job Type
Full-time
Career Level
Senior
