Manufacturing Manager, Liso-cel CAR-T, Manufacturing Operations

Bristol Myers Squibb•Summit, NJ

11d•$103,560 - $125,495•Onsite

About The Position

At Bristol Myers Squibb, our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team. The purpose of the Manufacturing Manger role is to manage and provide oversight of a Work Centered Team (WCT) whose primary responsibility is the execution of Cell Therapy manufacturing processes. The Manufacturing Manager is responsible to ensure their WCT members maintain a culture of safety, compliance, innovation, and Continuous Improvement within the Manufacturing Operations function. This position reports Senior Manager, Manufacturing.

Requirements

Strong people-management skills supported by two years of experience.
Extensive knowledge of EHS and cGMPs and the know–how to work and manage within a regulated environment.
Demonstrates aptitude for biotechnology principles and manufacturing systems.
Demonstrated proficiency in selection of team and effectively managing personnel issues.
Adaptable to a fast paced, complex, and ever-changing business environment.
Knowledge of lean manufacturing principles required.
Excellent communication skills
Bachelor’s degree in life sciences, engineering, biotechnology, or a related discipline, or an equivalent combination of education and relevant manufacturing experience.
Experience working in a regulated cGMP manufacturing environment, preferably within biologics, cell therapy, aseptic processing, or pharmaceutical manufacturing.
Demonstrated understanding of manufacturing documentation, batch record execution, deviation management, change control, CAPA processes, and data integrity expectations.
Ability to lead in a fast-paced, patient-focused manufacturing environment while maintaining strong attention to quality, safety, compliance, and schedule adherence.
Strong people management skills, including coaching, performance management, conflict resolution, accountability, team engagement, and employee development.
Effective communication and collaboration skills with the ability to partner across functions, escalate risks appropriately, and influence without direct authority.

Nice To Haves

Prior managerial leadership experience in CAR-T, cell therapy, biologics, or aseptic manufacturing operations.
Experience supporting commercial manufacturing operations, operational readiness, training qualification, and inspection readiness activities.
Knowledge of Lean manufacturing, visual management, tiered communication, Gemba, root cause analysis, and continuous improvement tools.
Experience managing shift-based teams, schedules, staffing plans, training plans, and resource allocation in a manufacturing environment.

Responsibilities

Ensure compliant execution of commercial CAR-T manufacturing operations in accordance with cGMP requirements, approved SOPs, work instructions, batch records, and quality standards.
Maintain hands-on manufacturing expertise and provide technical guidance, training, coaching, and real-time operational support to ensure successful product execution and schedule adherence.
Gain and maintain full process qualification, supporting manufacturing activities as needed to ensure operational flexibility, team capability, and production continuity.
Drive a strong safety culture through leadership presence, shopfloor engagement, Gemba activities, risk identification, hazard mitigation, and adherence to workplace safety practices.
Oversee batch record review, manufacturing documentation, and data integrity compliance, ensuring adherence to ALCOA+ principles and right-first-time performance.
Manage workforce planning, staffing, scheduling, hiring, onboarding, performance management, training compliance, and employee development to ensure operational readiness.
Monitor and communicate operational performance through KPIs, production metrics, tier meetings, performance reviews, and resource planning activities.
Ensure completion of all site-required standards and expectations, including required training, safety activities, quality culture expectations, walkthroughs, operational readiness activities, and applicable compliance requirements.
Partner cross-functionally with Quality, Supply Chain, Warehouse, Manufacturing Science & Technology, and other stakeholders to maintain compliant and efficient manufacturing processes.
Lead deviation management, root cause analysis, CAPAs, change controls, and continuous improvement initiatives to reduce risk, improve performance, and prevent recurrence.
Champion Lean manufacturing principles, visual management, problem-solving methodologies, and coaching practices to drive operational excellence and employee engagement.
Manage departmental resources and expenses, ensuring effective utilization of personnel, equipment, materials, and budget.
Identify, escalate, and mitigate operational risks that could impact product quality, compliance, patient safety, or production continuity.

Benefits

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include:
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.