Manufacturing Chemist 1

Illumina•San Diego, CA

35d•Onsite

About The Position

Seeking a highly motivated and team-oriented Manufacturing Chemist with experience in organic synthesis to join our Nucleotide Manufacturing group. Manufacture and test components and reagents of moderate to high complexity in a quality manner on standard laboratory equipment by following work instructions and test methods. The candidate must have a strong understanding of purification and analytical techniques used in the manufacture of complex nucleotides and/or oligonucleotides, such as Ion Exchange and Reverse Phase Chromatography. The candidate should have 0- 2 years of chemistry bench experience in synthetic processes.

Requirements

0-2 years of experience in synthetic chemistry processes, purification, and QC analysis of organic molecules.
Familiarity with standard laboratory equipment (HPLCs/UPLCs, synthesizers, reactors, rotary evaporators, UV/Vis spectrophotometers, pH meters, etc)
Solid technical knowledge of synthetic organic chemistry, HPLC methods, manufacturing processes, and manufacturing execution systems.
Ability to work with ERP, EAM, MES, and Quality systems (SAP, Camstar, Teamcenter, etc)
Excellent written and verbal communication skills required.
Basic understanding of equipment/instrument upkeep, calibration, and maintenance policies.
Ability to carry up to 40 lbs

Nice To Haves

Typically requires a Bachelor’s degree and a minimum of 0-2 years of related experience; or equivalent work experience.

Responsibilities

Follow all SOP's and WI's as required by the Quality Management System Plan and execute daily work with occasional supervision
Assemble data for analysis using accepted methods
Assess results of work and compare data against identifiable factors.
Summarize work accurately.
Determine appropriate action(s) by exercising judgement within defined procedures and practices.
Follow all safety rules at Illumina and apply all relevant protocols to work responsibilities
Executes simple experiments (troubleshooting, OOE, OOS, etc) designed by senior lab personnel
Identify non-conformances in work
Use basic Operational Excellence tools to identify root cause of problems
Completes ERP and MES transactions for manufacturing work order processing
Synthesizes molecules using industry standard instrumentation and techniques.
May perform purification of synthesized molecules, while monitoring performance through analysis of chromatograms.
May collect, prepare, and analyze product fractions using analytical HPLC techniques to determine product quality.
Measures and adjusts product concentration or mix by using applicable instrumentation.
Formulates buffers required for processing and storing target molecules throughout production.