Manufacturing Associate I-II

Artiva Biotherapeutics•San Diego, CA

2d•$75,000 - $105,000•Onsite

About The Position

Join Artiva Biotherapeutics in San Diego and work directly on the manufacturing floor to produce our innovative, off-the-shelf cell therapies in a state-of-the-art cGMP facility. Apply your expertise across cell culture, aseptic processing, harvest and fill-finish, playing a direct role in advancing therapies for patients with autoimmune diseases. The successful candidate will play a key role in the manufacturing of cell therapies internally at Artiva. He/ she will execute hands-on manufacturing processes to deliver new revolutionary therapeutics. The ideal candidate will demonstrate in-depth knowledge of cGMP compliance, strong hands-on laboratory skills and work in a high-performing team of manufacturing associates.

Requirements

Bachelor’s degree in a relevant science or engineering discipline, or equivalent work experience.
Minimum 1 year of cGMP biologics or cell culture manufacturing experience; biotech or cell therapy experience preferred.
Knowledge of cGMP regulations and FDA guidance applicable to biologics and cell therapy manufacturing.
Innovative, adaptable, and able to apply best practices in a small, growing environment.
Self-motivated with strong ownership, organizational skills, and the ability to prioritize and deliver results on time.

Nice To Haves

Aseptic gowning and ISO 7 cleanroom manufacturing
Cell counting platforms
Cell culture and expansion using bag systems and single-use large-scale bioreactors; Sartorius experience a plus
Lentiviral transduction
Automated and manual cell harvesting/washing; LOVO experience a plus
Cell selection/depletion using Miltenyi CliniMACS Prodigy
Fill-finish and cryopreservation in bags and vials; M1 filler and AT-vial experience a plus

Responsibilities

Execute GMO manufacturing operations including cell expansion, harvest, and fill-finish.
Perform Aseptic Process Validation and participate in annual aseptic qualification.
Follow cGMP standards and procedures to maintain compliance.
Support development of batch records, workflows, and SOPs in accordance with regulatory and GMP requirements.
Apply cell culture expertise to media/buffer preparation, cell passaging, bioreactor production, and harvesting.
Lead after-action reviews to improve operational efficiency and KPIs, identify process gaps/risks, and implement sustainable improvements.
Support equipment and process change controls through implementation.
Work in Grade B and Grade C cleanroom environments.
Perform hands-on manufacturing operations directly on the floor.