Manager, Upstream Process Development and Scale-up

Danaher•Marlborough, MA

11d•Onsite

About The Position

Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Cytiva, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact. You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life. Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. Take your next step to an altogether life-changing career. Learn about the Danaher Business System which makes everything possible. The Upstream Team Manager is responsible for leading the Fast Trak Process Development Services (PDS) Upstream team, providing technical, operational, and people leadership to deliver high-quality process development, scale-up, technology transfer, training, and customer support activities. This role serves as a key technical leader and customer-facing subject matter expert supporting biologics, viral vector, pDNA, and emerging therapeutic modalities. This position is part of the Fast Trak Process Development Services organization and will be located in Marlborough, Massachusetts.

Requirements

Bachelor’s degree or higher (MS or PhD preferred) in chemical engineering, molecular biology, biochemistry, or related discipline with 10+ years of relevant experience in biologics with 2+ years of direct experience leading technical teams and/or people management responsibilities.
Demonstrated hands-on expertise in upstream process development, scale-up, technology transfer, and mammalian cell culture operations ranging from laboratory to pilot scale.
Experience managing customer-facing projects and cross-functional teams with strong technical writing and presentation skills.
People leader that fosters a culture of safety, accountability, inclusion, collaboration, continuous improvement, and scientific excellence.

Responsibilities

Lead planning, execution, and delivery of upstream process development, scale-up, and technology transfer activities for biologics, viral vectors, plasmid DNA, mRNA, and other advanced therapy modalities.
Provide technical oversight and scientific leadership for cell culture bioreactor operations, process characterization and scale-up activities, and serve as a technical subject matter expert (SME) during customer meetings, project reviews, technical investigations, risk assessments, and troubleshooting activities.
Support the development of innovative service offerings, technologies, and workflows that expand Fast Trak capabilities and customer value.
Support proposal development, scope definition, technical reviews, customer presentations, and drive robust documentation practices including SOPs, study plans, batch records, investigations, technical reports, and technology transfer documentation.
Partner closely with downstream, analytics, applications, automation, R&D, commercial, and PMO teams to ensure successful project execution and foster scientific collaborations within Fast Trak PD, cross-functional teams, and customers to drive efficient execution of internal and external KPIs.
Lead and support workforce planning, talent development, recruitment, onboarding, succession planning, and ensure effective resource allocation and project prioritization to meet customer and business objectives.
Drive on-time delivery, quality, productivity, continuous improvement initiatives, and customer satisfaction metrics utilizing Danaher Business System (DBS) principles and tools.