Manager, Project Management - Large Molecule
About The Position
At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for a Manager, Project Management – Large Molecules on the Project and Strategy Management team to help us expand what’s possible for patients with serious diseases. Reporting to the Senior Director, Project & Strategy Management, you’ll drive large molecule (biologics) pipeline projects from research transition through process development, characterization, registration, and commercial readiness; leading cross-functional CMC teams across drug substance and drug product workstreams, and partnering with CDMOs to ensure high-quality delivery.
Requirements
- Bachelor’s degree
- 5 years of experience in project management experience in large molecule/biologics development
- Working knowledge of upstream/downstream processing and drug product/fill-finish
- Strong people and team leadership skills, with the ability to motivate and guide cross-functional teams without formal authority
- Proficiency with project management tools (e.g., MS Project, Excel, PowerPoint)
Nice To Haves
- PMP certification
- Experience with mAbs, recombinant proteins, or cell/gene therapy preferred
Responsibilities
- Lead large molecule project teams, internally and with CDMO/external partners, fostering collaboration and accountability.
- Guide biologics programs from Research through Technical Operations, tech transfer, regulatory submission, and launch
- Integrate across Drug Substance, Drug Product, Analytical Development, Quality, and Regulatory to align on project goals
- Drive structured frameworks for tech transfer, process characterization/validation, and comparability studies
- Identify and mitigate biologics-specific risks (e.g., cell line stability, viral safety, supply constraints)
- Own project planning, milestone tracking, and communication across key biologics milestones
- Represent Technical Operations in cross-functional and governance meetings
- Maintain communication and relationships with CDMOs and external partners to ensure alignment on timelines and deliverables
- Support budget planning and resource forecasting for biologics activities
- Contribute to a high-performing, people-centered project management culture
Benefits
- Comprehensive medical, dental, and vision coverage
- Mental health support
- Annual wellbeing reimbursement
- Access to our Employee Assistance Program (EAP)
- Generous paid time off policies
- Fertility and family-forming benefits
- Caregiver support
- Flexible work schedules with purposeful in-person collaboration
- 401(k) plan with a competitive company match
- Annual equity awards
- Participation in our Employee Stock Purchase Plan (ESPP)
- Company-paid life and disability insurance
- Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
- Employee resource groups
- Service and recognition programs
- Meaningful opportunities to connect, volunteer, and give back
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
