Manager, Finance and Accounting

LEXICON PHARMACEUTICALSThe Woodlands, TX
Hybrid

About The Position

Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Through our unique approach to gene science based on Nobel Prize-winning technology, we are moving forward rapidly to bring innovative therapies to market. At Lexicon, our passion and dedication are driven by the patients for whom we work. Lexicon employees are inspired by the idea that their work can improve patients' lives, and we know that our employees are essential to the success of our mission. Every day they bring their passion, talents, and dedication to an engaging environment where they are rewarded with opportunities to realize their potential. We are dedicated to making Lexicon a great place to work by providing employees with benefits, services, and programs as part of our total rewards package. Join our journey and be a part of our multitalented team and make a difference in patients’ lives! We have offices in The Woodlands, Texas and Bridgewater, New Jersey. We are seeking a highly motivated Manager of Finance and Accounting to join our team in The Woodlands, TX office. This role is hybrid.

Requirements

  • Bachelor’s degree in accounting, Finance or related field required
  • 4–6 years of public accounting experience or 5–8 years of industry experience in a public company
  • Proficient in GAAP
  • Moderate Excel skills (VLOOKUP, pivot tables, filters, etc.) required
  • Excellent communication and interpersonal skills; demonstrated ability to work collaboratively across a matrixed organization
  • Resourceful and proactive with strong detail orientation, analytical skills, and ability to drive projects forward

Nice To Haves

  • CPA Preferred
  • experienced in performing technical accounting research preferred
  • Experience with a large accounting system such as JDE, Oracle or SAP preferred
  • Experience with inventory accounting and/or clinical trial accruals preferred

Responsibilities

  • Oversee the general ledger, ensuring accurate, timely financial accounting.
  • Support internal and external reporting.
  • Oversee key audit activities.
  • Lead the SOX process, including control documentation and testing.
  • Prepare accruals for clinical and manufacturing activities and other high-risk areas.
  • Review journal entries prepared by accounting staff.
  • Reconcile finished goods and other inventories.
  • Analyze budget variances.
  • Support R&D budgeting in partnership with department heads.
  • Support the monthly accounting close by preparing certain entries (e.g. higher-risk clinical accruals, stock-based compensation entries, etc.) and reviewing other monthly journal entries and schedules prepared by staff/senior accountant(s).
  • Monitor progress against the close calendar.
  • Serve as point of contact with external auditors as part of the financial reporting and SOX audit processes.
  • Coordinate and compile audit documentation as needed for external/SOX audits across key areas, including cash, prepaids, legal accruals, debt, allocations, etc.
  • Review/prepare monthly general ledger account reconciliations to ensure accuracy, completeness, and compliance with accounting standards.
  • Review daily cash activity and review associated journal entries to maintain accurate cash reporting.
  • Generate and prepare monthly financial reports, including the trial balance, variance reports, and flash reports, to support internal and external reporting needs.
  • Prepare select SEC disclosures as required.
  • Completes ad hoc projects as needed.

Benefits

  • benefits, services, and programs as part of our total rewards package
© 2026 Teal Labs, Inc
Privacy PolicyTerms of Service